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Pembrolizumab as Second-Line Therapy for Advanced Urothelial Carcinoma.
Bellmunt J, de Wit R, Vaughn DJ, Fradet Y, Lee JL, Fong L, Vogelzang NJ, Climent MA, Petrylak DP, Choueiri TK, Necchi A, Gerritsen W, Gurney H, Quinn DI, Culine S, Sternberg CN, Mai Y, Poehlein CH, Perini RF, Bajorin DF; KEYNOTE-045 Investigators. Bellmunt J, et al. N Engl J Med. 2017 Mar 16;376(11):1015-1026. doi: 10.1056/NEJMoa1613683. Epub 2017 Feb 17. N Engl J Med. 2017. PMID: 28212060 Free PMC article. Clinical Trial.
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S, Hao K, Feenstra B, Wood AR, Mahajan A, Tyrrell J, Robertson NR, Rayner NW, Qiao Z, Moen GH, Vaudel M, Marsit CJ, Chen J, Nodzenski M, Schnurr TM, Zafarmand MH, Bradfield JP, Grarup N, Kooijman MN, Li-Gao R, Geller F, Ahluwalia TS, Paternoster L, Rueedi R, Huikari V, Hottenga JJ, Lyytikäinen LP, Cavadino A, Metrustry S, Cousminer DL, Wu Y, Thiering E, Wang CA, Have CT, Vilor-Tejedor N, Joshi PK, Painter JN, Ntalla I, Myhre R, Pitkänen N, van Leeuwen EM, Joro R, Lagou V, Richmond RC, Espinosa A, Barton SJ, Inskip HM, Holloway JW, Santa-Marina L, Estivill X, Ang W, Marsh JA, Reichetzeder C, Marullo L, Hocher B, Lunetta KL, Murabito JM, Relton CL, Kogevinas M, Chatzi L, Allard C, Bouchard L, Hivert MF, Zhang G, Muglia LJ, Heikkinen J; EGG Consortium; Morgen CS, van Kampen AHC, van Schaik BDC, Mentch FD, Langenberg C, Luan J, Scott RA, Zhao JH, Hemani G, Ring SM, Bennett AJ, Gaulton KJ, Fernandez-Tajes J, van Zuydam NR, Medina-Gomez C, de Haan HG, Rosendaal FR, Kutalik Z, Marques-Vidal P, Das S, Willemsen G, Mbarek H, Müller-Nurasyid M, Standl M, Appel EVR, Fonvig CE, Trier C, van Beijsterveldt C… See abstract for full author list ➔ Warrington NM, et al. Nat Genet. 2019 May;51(5):804-814. doi: 10.1038/s41588-019-0403-1. Epub 2019 May 1. Nat Genet. 2019. PMID: 31043758 Free PMC article.
Clinical Profiles and Patterns of Kidney Disease Progression in C3 Glomerulopathy.
Caravaca-Fontán F, Cavero T, Díaz-Encarnación M, Cabello V, Ariceta G, Quintana LF, Marco H, Barros X, Ramos N, Rodríguez-Mendiola N, Cruz S, Fernández-Juárez G, Rodríguez A, Pérez de José A, Rabasco C, Rodado R, Fernández L, Pérez-Gómez V, Ávila A, Bravo L, Espinosa N, Allende N, Sanchez de la Nieta MD, Rodríguez E, Rivas B, Melgosa M, Huerta A, Miquel R, Mon C, Fraga G, de Lorenzo A, Draibe J, González F, Shabaka A, López-Rubio ME, Fenollosa MÁ, Martín-Penagos L, Da Silva I, Titos JA, Rodríguez de Córdoba S, Goicoechea de Jorge E, Praga M; Spanish Group for the Study of Glomerular Diseases (GLOSEN). Caravaca-Fontán F, et al. Kidney360. 2023 May 1;4(5):659-672. doi: 10.34067/KID.0000000000000115. Epub 2023 Mar 30. Kidney360. 2023. PMID: 36996481 Free PMC article.
Kidney survival was significantly higher in patients with a chronicity score <4 and proteinuria <3.5 g/d, both in those presenting with an eGFR under/above 30 ml/min per 1.73 m(2). The median eGFR slope of patients who reached kidney failure was 6.5 ml/min per 1.73 …
Kidney survival was significantly higher in patients with a chronicity score <4 and proteinuria <3.5 g/d, both in those presenting wit …
Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas.
Bredel M, Espinosa L, Kim H, Scholtens DM, McElroy JP, Rajbhandari R, Meng W, Kollmeyer TM, Malta TM, Quezada MA, Harsh GR, Lobo-Jarne T, Solé L, Merati A, Nagaraja S, Nair S, White JJ, Thudi NK, Fleming JL, Webb A, Natsume A, Ogawa S, Weber RG, Bertran J, Haque SJ, Hentschel B, Miller CR, Furnari FB, Chan TA, Grosu AL, Weller M, Barnholtz-Sloan JS, Monje M, Noushmehr H, Jenkins RB, Rogers CL, MacDonald DR, Pugh SL, Chakravarti A. Bredel M, et al. Cell Rep Med. 2023 Jun 20;4(6):101082. doi: 10.1016/j.xcrm.2023.101082. Cell Rep Med. 2023. PMID: 37343523 Free PMC article.
Adjuvant dabrafenib and trametinib for patients with resected BRAF -mutated melanoma: DESCRIBE-AD real-world retrospective observational study.
Manzano JL, Martin-Liberal J, Fernández-Morales LA, Benítez G, Medina Martínez J, Quindós M, García-Castaño A, Fernández O, Simo RV, Majem M, Bellido L, Ayala de Miguel P, Campos B, Espinosa E, Macías Cerrolaza JA, Gil-Arnaiz I, Lorente D, Rodriguez-Lescure A, Perez VN, López Castro R, Gramaje MG, Puértolas T, Rodriguez Moreno JF, Espasa Font L, Belaustegui Ferrández G, Cerezuela-Fuentes P. Manzano JL, et al. Melanoma Res. 2023 Oct 1;33(5):388-397. doi: 10.1097/CMR.0000000000000888. Epub 2023 Mar 28. Melanoma Res. 2023. PMID: 36988401 Free PMC article.
Long-Term Exposure to Air Pollution and COVID-19 Vaccine Antibody Response in a General Population Cohort (COVICAT Study, Catalonia).
Kogevinas M, Karachaliou M, Espinosa A, Aguilar R, Castaño-Vinyals G, Garcia-Aymerich J, Carreras A, Cortés B, Pleguezuelos V, Papantoniou K, Rubio R, Jiménez A, Vidal M, Serra P, Parras D, Santamaría P, Izquierdo L, Cirach M, Nieuwenhuijsen M, Dadvand P, Straif K, Moncunill G, de Cid R, Dobaño C, Tonne C. Kogevinas M, et al. Environ Health Perspect. 2023 Apr;131(4):47001. doi: 10.1289/EHP11989. Epub 2023 Apr 5. Environ Health Perspect. 2023. PMID: 37017430 Free PMC article.
We drew blood samples in 2021 from 1,090 participants of 2,404 who provided samples in 2020, and we included 927 participants in this analysis. We measured immunoglobulin M (IgM), IgG, and IgA antibodies against five viral-target antigens, including receptor-binding domain …
We drew blood samples in 2021 from 1,090 participants of 2,404 who provided samples in 2020, and we included 927 participants in this analys …
It is time to define an organizational model for the prevention and management of infections along the surgical pathway: a worldwide cross-sectional survey.
Sartelli M, Labricciosa FM, Coccolini F, Coimbra R, Abu-Zidan FM, Ansaloni L, Al-Hasan MN, Ansari S, Barie PS, Caínzos MA, Ceresoli M, Chiarugi M, Claridge JA, Cicuttin E, Dellinger EP, Fry DE, Guirao X, Hardcastle TC, Hecker A, Leppäniemi AK, Litvin A, Marwah S, Maseda E, Mazuski JE, Memish ZA, Kirkpatrick AW, Pagani L, Podda M, Rasa HK, Sakakushev BE, Sawyer RG, Tumietto F, Xiao Y, Aboubreeg WF, Adamou H, Akhmeteli L, Akin E, Alberio MG, Alconchel F, Magagi IA, Araúz AB, Argenio G, Atanasov BC, Atici SD, Awad SS, Baili E, Bains L, Bala M, Baraket O, Baral S, Belskii VA, Benboubker M, Ben-Ishay O, Bordoni P, Boumédiène A, Brisinda G, Cavazzuti L, Chandy SJ, Chiarello MM, Cillara N, Clarizia G, Cocuz ME, Cocuz IG, Conti L, Coppola R, Cui Y, Czepiel J, D'Acapito F, Damaskos D, Das K, De Simone B, Delibegovic S, Demetrashvili Z, Detanac DS, Dhingra S, Di Bella S, Dimitrov EN, Dogjani A, D'Oria M, Dumitru IM, Elmangory MM, Enciu O, Fantoni M, Filipescu D, Fleres F, Foghetti D, Fransvea P, Gachabayov M, Galeiras R, Gattuso G, Ghannam WM, Ghisetti V, Giraudo G, Gonfa KB, Gonullu E, Hamad YTEY, Hecker M, Isik A, Ismail N, Ismail A, Jain SA, Kanj SS, Kapoor G, Karaiskos I, Kavalakat AJ, … See abstract for full author list ➔ Sartelli M, et al. World J Emerg Surg. 2022 Mar 17;17(1):17. doi: 10.1186/s13017-022-00420-4. World J Emerg Surg. 2022. PMID: 35300731 Free PMC article.
Green spaces, excess weight and obesity in Spain.
O'Callaghan-Gordo C, Espinosa A, Valentin A, Tonne C, Pérez-Gómez B, Castaño-Vinyals G, Dierssen-Sotos T, Moreno-Iribas C, de Sanjose S, Fernandez-Tardón G, Vanaclocha-Espi M, Chirlaque MD, Cirach M, Aragonés N, Gómez-Acebo I, Ardanaz E, Moreno V, Pollan M, Bustamante M, Nieuwenhuijsen MJ, Kogevinas M. O'Callaghan-Gordo C, et al. Int J Hyg Environ Health. 2020 Jan;223(1):45-55. doi: 10.1016/j.ijheh.2019.10.007. Epub 2019 Nov 1. Int J Hyg Environ Health. 2020. PMID: 31679857
We geocoded current residences and defined exposures in a buffer of 300 m around them: i) access to green space, identified using Urban Atlas, and ii) levels of surrounding greenness, measured by the Normalized Difference Vegetation Index. ...
We geocoded current residences and defined exposures in a buffer of 300 m around them: i) access to green space, identified using Urb …
Marine heatwaves drive recurrent mass mortalities in the Mediterranean Sea.
Garrabou J, Gómez-Gras D, Medrano A, Cerrano C, Ponti M, Schlegel R, Bensoussan N, Turicchia E, Sini M, Gerovasileiou V, Teixido N, Mirasole A, Tamburello L, Cebrian E, Rilov G, Ledoux JB, Souissi JB, Khamassi F, Ghanem R, Benabdi M, Grimes S, Ocaña O, Bazairi H, Hereu B, Linares C, Kersting DK, la Rovira G, Ortega J, Casals D, Pagès-Escolà M, Margarit N, Capdevila P, Verdura J, Ramos A, Izquierdo A, Barbera C, Rubio-Portillo E, Anton I, López-Sendino P, Díaz D, Vázquez-Luis M, Duarte C, Marbà N, Aspillaga E, Espinosa F, Grech D, Guala I, Azzurro E, Farina S, Cristina Gambi M, Chimienti G, Montefalcone M, Azzola A, Mantas TP, Fraschetti S, Ceccherelli G, Kipson S, Bakran-Petricioli T, Petricioli D, Jimenez C, Katsanevakis S, Kizilkaya IT, Kizilkaya Z, Sartoretto S, Elodie R, Ruitton S, Comeau S, Gattuso JP, Harmelin JG. Garrabou J, et al. Glob Chang Biol. 2022 Oct;28(19):5708-5725. doi: 10.1111/gcb.16301. Epub 2022 Jul 18. Glob Chang Biol. 2022. PMID: 35848527 Free PMC article.
These MMEs affected thousands of kilometers of coastline from the surface to 45 m, across a range of marine habitats and taxa (50 taxa across 8 phyla). ...
These MMEs affected thousands of kilometers of coastline from the surface to 45 m, across a range of marine habitats and taxa (50 tax …
SEOM clinical guideline for the management of cutaneous melanoma (2020).
Majem M, Manzano JL, Marquez-Rodas I, Mujika K, Muñoz-Couselo E, Pérez-Ruiz E, de la Cruz-Merino L, Espinosa E, Gonzalez-Cao M, Berrocal A. Majem M, et al. Clin Transl Oncol. 2021 May;23(5):948-960. doi: 10.1007/s12094-020-02539-9. Epub 2021 Mar 2. Clin Transl Oncol. 2021. PMID: 33651321 Free PMC article.
33 results