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Page 1
2-Carboranylquinazoline: The Path to an ABCG2 Inhibitor.
ChemMedChem. 2023 Jun 1;18(11):e202300094. doi: 10.1002/cmdc.202300094. Epub 2023 Apr 14.
ChemMedChem. 2023.
PMID: 36988057
Borcalein: a Carborane-Based Analogue of Baicalein with 12-Lipoxygenase-Independent Toxicity.
Kuhnert R, Kuhnert L, Sárosi MB, George S, Draca D, Paskas S, Hofmann B, Steinhilber D, Honscha W, Mijatović S, Maksimović-Ivanić D, Hey-Hawkins E.
Kuhnert R, et al. Among authors: kuhnert l.
ChemMedChem. 2022 Jan 5;17(1):e202100588. doi: 10.1002/cmdc.202100588. Epub 2021 Nov 11.
ChemMedChem. 2022.
PMID: 34694057
Free PMC article.
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Carborane-Based ABCG2-Inhibitors Sensitize ABC-(Over)Expressing Cancer Cell Lines for Doxorubicin and Cisplatin.
Paskas S, Stockmann P, Mijatović S, Kuhnert L, Honscha W, Hey-Hawkins E, Maksimović-Ivanić D.
Paskas S, et al. Among authors: kuhnert l.
Pharmaceuticals (Basel). 2023 Nov 9;16(11):1582. doi: 10.3390/ph16111582.
Pharmaceuticals (Basel). 2023.
PMID: 38004447
Free PMC article.
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AhR-activating pesticides increase the bovine ABCG2 efflux activity in MDCKII-bABCG2 cells.
Kuhnert L, Giantin M, Dacasto M, Halwachs S, Honscha W.
Kuhnert L, et al.
PLoS One. 2020 Aug 7;15(8):e0237163. doi: 10.1371/journal.pone.0237163. eCollection 2020.
PLoS One. 2020.
PMID: 32764792
Free PMC article.
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The More the Better-Investigation of Polymethoxylated N-Carboranyl Quinazolines as Novel Hybrid Breast Cancer Resistance Protein Inhibitors.
Stockmann P, Kuhnert L, Leinung W, Lakoma C, Scholz B, Paskas S, Mijatović S, Maksimović-Ivanić D, Honscha W, Hey-Hawkins E.
Stockmann P, et al. Among authors: kuhnert l.
Pharmaceutics. 2023 Jan 10;15(1):241. doi: 10.3390/pharmaceutics15010241.
Pharmaceutics. 2023.
PMID: 36678870
Free PMC article.
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Enhanced reversal of ABCG2-mediated drug resistance by replacing a phenyl ring in baicalein with a meta-carborane.
Kuhnert L, Kuhnert R, Sárosi MB, Lakoma C, Scholz BK, Lönnecke P, Hey-Hawkins E, Honscha W.
Kuhnert L, et al.
Mol Oncol. 2024 Feb;18(2):280-290. doi: 10.1002/1878-0261.13527. Epub 2023 Oct 5.
Mol Oncol. 2024.
PMID: 37727134
Free PMC article.
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Carboranes as Potent Phenyl Mimetics: A Comparative Study on the Reversal of ABCG2-Mediated Drug Resistance by Carboranylquinazolines and Their Organic Isosteres.
Stockmann P, Kuhnert L, Krajnović T, Mijatović S, Maksimović-Ivanić D, Honscha W, Hey-Hawkins E.
Stockmann P, et al. Among authors: kuhnert l.
ChemMedChem. 2024 Jan 15;19(2):e202300506. doi: 10.1002/cmdc.202300506. Epub 2023 Dec 11.
ChemMedChem. 2024.
PMID: 38012078
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