Luisa Leitzbach - Search Results

Year	Number of Results
2021	2
2022	4
2023	2
2024	0

1

Dual Piperidine-Based Histamine H₃ and Sigma-1 Receptor Ligands in the Treatment of Nociceptive and Neuropathic Pain.

Szczepańska K, Karcz T, Dichiara M, Mogilski S, Kalinowska-Tłuścik J, Pilarski B, Leniak A, Pietruś W, Podlewska S, Popiołek-Barczyk K, Humphrys LJ, Ruiz-Cantero MC, Reiner-Link D, Leitzbach L, Łażewska D, Pockes S, Górka M, Zmysłowski A, Calmels T, Cobos EJ, Marrazzo A, Stark H, Bojarski AJ, Amata E, Kieć-Kononowicz K. Szczepańska K, et al. Among authors: leitzbach l. J Med Chem. 2023 Jul 27;66(14):9658-9683. doi: 10.1021/acs.jmedchem.3c00430. Epub 2023 Jul 7. J Med Chem. 2023. PMID: 37418295 Free PMC article.

2

Substituted Purines as High-Affinity Histamine H₃ Receptor Ligands.

Espinosa-Bustos C, Leitzbach L, Añazco T, Silva MJ, Campo AD, Castro-Alvarez A, Stark H, Salas CO. Espinosa-Bustos C, et al. Among authors: leitzbach l. Pharmaceuticals (Basel). 2022 May 4;15(5):573. doi: 10.3390/ph15050573. Pharmaceuticals (Basel). 2022. PMID: 35631399 Free PMC article.

3

Evaluation of chromane derivatives: Promising privileged scaffolds for lead discovery within Alzheimer's disease.

Moutayakine A, Marques C, López Ó, Bagetta D, Leitzbach L, Hagenow S, Carreiro EP, Stark H, Alcaro S, Fernández-Bolaños JG, Burke AJ. Moutayakine A, et al. Among authors: leitzbach l. Bioorg Med Chem. 2022 Aug 15;68:116807. doi: 10.1016/j.bmc.2022.116807. Epub 2022 May 9. Bioorg Med Chem. 2022. PMID: 35653868

4

Repurposing of 8-Hydroxyquinoline-Based Butyrylcholinesterase and Cathepsin B Ligands as Potent Nonpeptidic Deoxyribonuclease I Inhibitors.

Gajic M, Knez D, Sosič I, Mravljak J, Meden A, Košak U, Leitzbach L, George S, Hofmann B, Zivkovic A, Steinhilber D, Stark H, Gobec S, Smelcerovic A, Anderluh M. Gajic M, et al. Among authors: leitzbach l. ChemMedChem. 2022 Mar 4;17(5):e202100694. doi: 10.1002/cmdc.202100694. Epub 2022 Feb 3. ChemMedChem. 2022. PMID: 34994078

5

Guided rational design with scaffold hopping leading to novel histamine H₃ receptor ligands.

Ghamari N, Kouhi Hargelan S, Zivkovic A, Leitzbach L, Dastmalchi S, Stark H, Hamzeh-Mivehroud M. Ghamari N, et al. Among authors: leitzbach l. Bioorg Chem. 2021 Dec;117:105411. doi: 10.1016/j.bioorg.2021.105411. Epub 2021 Oct 8. Bioorg Chem. 2021. PMID: 34653944

6

Multitargeting approaches to cognitive impairment: Synthesis of aryl-alkylpiperazines and assessment at cholinesterases, histamine H₃ and dopamine D₃ receptors.

Aranha CMSQ, Reiner-Link D, Leitzbach LR, Lopes FB, Stark H, Fernandes JPS. Aranha CMSQ, et al. Among authors: leitzbach lr. Bioorg Med Chem. 2023 Jan 15;78:117132. doi: 10.1016/j.bmc.2022.117132. Epub 2022 Dec 16. Bioorg Med Chem. 2023. PMID: 36542960

7

Ugi Reaction Synthesis of Oxindole-Lactam Hybrids as Selective Butyrylcholinesterase Inhibitors.

Brandão P, López Ó, Leitzbach L, Stark H, Fernández-Bolaños JG, Burke AJ, Pineiro M. Brandão P, et al. Among authors: leitzbach l. ACS Med Chem Lett. 2021 Jul 23;12(11):1718-1725. doi: 10.1021/acsmedchemlett.1c00344. eCollection 2021 Nov 11. ACS Med Chem Lett. 2021. PMID: 34795859 Free PMC article.

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