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A recombinant SARS-CoV-2 receptor-binding domain expressed in an engineered fungal strain of Thermothelomyces heterothallica induces a functional immune response in mice.
Lazo L, Bequet-Romero M, Lemos G, Musacchio A, Cabrales A, Bruno AJ, Ariel Espinosa L, Saloheimo M, Vitikainen M, Hernández A, Emalfarb M, Tchelet R, Suzarte E, Guillén G. Lazo L, et al. Among authors: ariel espinosa l. Vaccine. 2022 Feb 16;40(8):1162-1169. doi: 10.1016/j.vaccine.2022.01.007. Epub 2022 Jan 19. Vaccine. 2022. PMID: 35078661 Free PMC article.
Chimeric Antigen by the Fusion of SARS-CoV-2 Receptor Binding Domain with the Extracellular Domain of Human CD154: A Promising Improved Vaccine Candidate.
Ávalos I, Lao T, Rodríguez EM, Zamora Y, Rodríguez A, Ramón A, Lemos G, Cabrales A, Bequet-Romero M, Casillas D, Andújar I, Espinosa LA, González LJ, Alvarez Y, Carpio Y, Estrada MP. Ávalos I, et al. Among authors: espinosa la. Vaccines (Basel). 2022 Jun 3;10(6):897. doi: 10.3390/vaccines10060897. Vaccines (Basel). 2022. PMID: 35746505 Free PMC article.
Synthesis, LC-MS/MS analysis, and biological evaluation of two vaccine candidates against ticks based on the antigenic P0 peptide from R. sanguineus linked to the p64K carrier protein from Neisseria meningitidis.
González LJ, Encinosa Guzmán PE, Machado W, Pousa S, Leyva A, Arguelles ALC, Cabrera G, Espinosa LA, Parra R, Hernández R, Soto YB, Ledesma FL, Joglar M, Guirola O, Kurt LU, Carvalho PC, Cabrales A, Garay H, Besada V, Durán R, Takao T, Estrada MP, Rodríguez-Mallon A. González LJ, et al. Among authors: espinosa la. Anal Bioanal Chem. 2021 Sep;413(23):5885-5900. doi: 10.1007/s00216-021-03569-0. Epub 2021 Aug 3. Anal Bioanal Chem. 2021. PMID: 34341841 Free PMC article.
In-solution buffer-free digestion allows full-sequence coverage and complete characterization of post-translational modifications of the receptor-binding domain of SARS-CoV-2 in a single ESI-MS spectrum.
Espinosa LA, Ramos Y, Andújar I, Torres EO, Cabrera G, Martín A, Roche D, Chinea G, Becquet M, González I, Canaán-Haden C, Nelson E, Rojas G, Pérez-Massón B, Pérez-Martínez D, Boggiano T, Palacio J, Lozada Chang SL, Hernández L, de la Luz Hernández KR, Markku S, Vitikainen M, Valdés-Balbín Y, Santana-Medero D, Rivera DG, Vérez-Bencomo V, Emalfarb M, Tchelet R, Guillén G, Limonta M, Pimentel E, Ayala M, Besada V, González LJ. Espinosa LA, et al. Anal Bioanal Chem. 2021 Dec;413(30):7559-7585. doi: 10.1007/s00216-021-03721-w. Epub 2021 Nov 5. Anal Bioanal Chem. 2021. PMID: 34739558 Free PMC article.
Protein content of the Hylesia metabus egg nest setae (Cramer [1775]) (Lepidoptera: Saturniidae) and its association with the parental investment for the reproductive success and lepidopterism.
Cabrera G, Lundberg U, Rodríguez-Ulloa A, Herrera M, Machado W, Portela M, Palomares S, Espinosa LA, Ramos Y, Durán R, Besada V, Vonasek E, González LJ. Cabrera G, et al. Among authors: espinosa la. J Proteomics. 2017 Jan 6;150:183-200. doi: 10.1016/j.jprot.2016.08.010. Epub 2016 Aug 25. J Proteomics. 2017. PMID: 27568362