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2019 | 1 |
2020 | 1 |
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Page 1
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
J Med Chem. 2024 Apr 11;67(7):5837-5853. doi: 10.1021/acs.jmedchem.4c00121. Epub 2024 Mar 27.
J Med Chem. 2024.
PMID: 38533580
Discovery of a Potent and Selective Fragment-like Inhibitor of Methyllysine Reader Protein Spindlin 1 (SPIN1).
Xiong Y, Greschik H, Johansson C, Seifert L, Bacher J, Park KS, Babault N, Martini M, Fagan V, Li F, Chau I, Christott T, Dilworth D, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Brennan P, Fedorov O, Jung M, Farnie G, Liu J, Oppermann U, Schüle R, Jin J.
Xiong Y, et al. Among authors: seifert l.
J Med Chem. 2019 Oct 24;62(20):8996-9007. doi: 10.1021/acs.jmedchem.9b00522. Epub 2019 Jul 24.
J Med Chem. 2019.
PMID: 31260300
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Structure-Based Design, Docking and Binding Free Energy Calculations of A366 Derivatives as Spindlin1 Inhibitors.
Luise C, Robaa D, Regenass P, Maurer D, Ostrovskyi D, Seifert L, Bacher J, Burgahn T, Wagner T, Seitz J, Greschik H, Park KS, Xiong Y, Jin J, Schüle R, Breit B, Jung M, Sippl W.
Luise C, et al. Among authors: seifert l.
Int J Mol Sci. 2021 May 31;22(11):5910. doi: 10.3390/ijms22115910.
Int J Mol Sci. 2021.
PMID: 34072837
Free PMC article.
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Epigenetics meets GPCR: inhibition of histone H3 methyltransferase (G9a) and histamine H3 receptor for Prader-Willi Syndrome.
Reiner D, Seifert L, Deck C, Schüle R, Jung M, Stark H.
Reiner D, et al. Among authors: seifert l.
Sci Rep. 2020 Aug 11;10(1):13558. doi: 10.1038/s41598-020-70523-y.
Sci Rep. 2020.
PMID: 32782417
Free PMC article.
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