Incidental diagnosis of a pancreatic adenocarcinoma in a woman affected by gestational diabetes mellitus: case report and literature review

Am J Obstet Gynecol MFM. 2021 Nov;3(6):100471. doi: 10.1016/j.ajogmf.2021.100471. Epub 2021 Aug 25.

Abstract

Pancreatic cancer is rarely diagnosed during pregnancy; it usually manifests with symptoms such as epigastric pain, vomiting, weight loss, and jaundice, rarely mimicking the hemolysis, elevated liver enzymes, and low platelet count syndrome. It has been postulated that there exists a correlation between the diagnosis of gestational diabetes mellitus and the occurrence of pancreatic cancer later in life. We conducted an expert literature review of the 31 available documented pancreatic cancer cases that were diagnosed during pregnancy. We also report pancreatic adenocarcinoma incidentally suspected in an asymptomatic woman affected by gestational diabetes mellitus; the woman was undergoing a fetal growth scan.

Keywords: gestational diabetes mellitus; growth scan; obesity; pancreatic cancer; pregnancy.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenocarcinoma* / diagnosis
  • Diabetes, Gestational* / diagnosis
  • Female
  • Humans
  • Pancreatic Neoplasms* / diagnosis
  • Pregnancy