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3D ECM-rich environment sustains the identity of naive human iPSCs.
Cesare E, Urciuolo A, Stuart HT, Torchio E, Gesualdo A, Laterza C, Gagliano O, Martewicz S, Cui M, Manfredi A, Di Filippo L, Sabatelli P, Squarzoni S, Zorzan I, Betto RM, Martello G, Cacchiarelli D, Luni C, Elvassore N. Cesare E, et al. Among authors: di filippo l. Cell Stem Cell. 2022 Dec 1;29(12):1703-1717.e7. doi: 10.1016/j.stem.2022.11.011. Cell Stem Cell. 2022. PMID: 36459970 Free article.
Therapeutic homology-independent targeted integration in retina and liver.
Tornabene P, Ferla R, Llado-Santaeularia M, Centrulo M, Dell'Anno M, Esposito F, Marrocco E, Pone E, Minopoli R, Iodice C, Nusco E, Rossi S, Lyubenova H, Manfredi A, Di Filippo L, Iuliano A, Torella A, Piluso G, Musacchia F, Surace EM, Cacchiarelli D, Nigro V, Auricchio A. Tornabene P, et al. Among authors: di filippo l. Nat Commun. 2022 Apr 12;13(1):1963. doi: 10.1038/s41467-022-29550-8. Nat Commun. 2022. PMID: 35414130 Free PMC article.
SARS-CoV-2 infection and replication in human gastric organoids.
Giobbe GG, Bonfante F, Jones BC, Gagliano O, Luni C, Zambaiti E, Perin S, Laterza C, Busslinger G, Stuart H, Pagliari M, Bortolami A, Mazzetto E, Manfredi A, Colantuono C, Di Filippo L, Pellegata AF, Panzarin V, Thapar N, Li VSW, Eaton S, Cacchiarelli D, Clevers H, Elvassore N, De Coppi P. Giobbe GG, et al. Among authors: di filippo l. Nat Commun. 2021 Nov 16;12(1):6610. doi: 10.1038/s41467-021-26762-2. Nat Commun. 2021. PMID: 34785679 Free PMC article.
HiCeekR: A Novel Shiny App for Hi-C Data Analysis.
Di Filippo L, Righelli D, Gagliardi M, Matarazzo MR, Angelini C. Di Filippo L, et al. Front Genet. 2019 Nov 4;10:1079. doi: 10.3389/fgene.2019.01079. eCollection 2019. Front Genet. 2019. PMID: 31749839 Free PMC article.
The Microfluidic Environment Reveals a Hidden Role of Self-Organizing Extracellular Matrix in Hepatic Commitment and Organoid Formation of hiPSCs.
Michielin F, Giobbe GG, Luni C, Hu Q, Maroni I, Orford MR, Manfredi A, Di Filippo L, David AL, Cacchiarelli D, De Coppi P, Eaton S, Elvassore N. Michielin F, et al. Among authors: di filippo l. Cell Rep. 2020 Dec 1;33(9):108453. doi: 10.1016/j.celrep.2020.108453. Cell Rep. 2020. PMID: 33264615 Free PMC article.