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Showing results for lucas dotti
Your search for Lucas Deotti retrieved no results
Switch to fulvestrant and palbociclib versus no switch in advanced breast cancer with rising ESR1 mutation during aromatase inhibitor and palbociclib therapy (PADA-1): a randomised, open-label, multicentre, phase 3 trial.
Bidard FC, Hardy-Bessard AC, Dalenc F, Bachelot T, Pierga JY, de la Motte Rouge T, Sabatier R, Dubot C, Frenel JS, Ferrero JM, Ladoire S, Levy C, Mouret-Reynier MA, Lortholary A, Grenier J, Chakiba C, Stefani L, Plaza JE, Clatot F, Teixeira L, D'Hondt V, Vegas H, Derbel O, Garnier-Tixidre C, Canon JL, Pistilli B, André F, Arnould L, Pradines A, Bièche I, Callens C, Lemonnier J, Berger F, Delaloge S; PADA-1 investigators. Bidard FC, et al. Lancet Oncol. 2022 Nov;23(11):1367-1377. doi: 10.1016/S1470-2045(22)00555-1. Epub 2022 Sep 29. Lancet Oncol. 2022. PMID: 36183733 Clinical Trial.
Randomised, open-label, multicentric phase III trial to evaluate the safety and efficacy of palbociclib in combination with endocrine therapy, guided by ESR1 mutation monitoring in oestrogen receptor-positive, HER2-negative metastatic breast cancer patients: study design of PADA-1.
Berger F, Marce M, Delaloge S, Hardy-Bessard AC, Bachelot T, Bièche I, Pradines A, De La Motte Rouge T, Canon JL, André F, Arnould L, Clatot F, Lemonnier J, Marques S, Bidard FC; PADA-1 investigators. Berger F, et al. BMJ Open. 2022 Mar 3;12(3):e055821. doi: 10.1136/bmjopen-2021-055821. BMJ Open. 2022. PMID: 35241469 Free PMC article. Clinical Trial.
Estrogen regulated proteases and antiproteases in ovarian and breast cancer cells.
Rochefort H, Chalbos D, Cunat S, Lucas A, Platet N, Garcia M. Rochefort H, et al. J Steroid Biochem Mol Biol. 2001 Jan-Mar;76(1-5):119-24. doi: 10.1016/s0960-0760(00)00142-4. J Steroid Biochem Mol Biol. 2001. PMID: 11384869 Review.
Cathepsin D (cath-D), an estrogen-regulated protease appears mostly to increase the number of tumor cells rather than their invasion or motility through the extracellular matrix. Estradiol is mitogenic but in vitro it also inhibits invasion and motility. ...
Cathepsin D (cath-D), an estrogen-regulated protease appears mostly to increase the number of tumor cells rather than their invasion or moti …
Differential effects of estrogen receptors in the rostral ventrolateral medulla in Goldblatt hypertension.
Maruyama NO, Estrela HF, Sales EBO, Lucas TF, Porto CS, Bergamaschi CT, Campos RR. Maruyama NO, et al. J Steroid Biochem Mol Biol. 2022 Nov;224:106176. doi: 10.1016/j.jsbmb.2022.106176. Epub 2022 Sep 7. J Steroid Biochem Mol Biol. 2022. PMID: 36087695 Free article.
Previous studies have shown that 17beta-estradiol plays a cardioprotective role in the central nervous system (CNS) of male rats. The aim of the present study was to determine the influence of 17beta-estradiol on sympathetic vasomotor activity and blood pressure in …
Previous studies have shown that 17beta-estradiol plays a cardioprotective role in the central nervous system (CNS) of male rats. The …
Estrogen receptor mediated inhibition of cancer cell invasion and motility: an overview.
Rochefort H, Platet N, Hayashido Y, Derocq D, Lucas A, Cunat S, Garcia M. Rochefort H, et al. J Steroid Biochem Mol Biol. 1998 Apr;65(1-6):163-8. doi: 10.1016/s0960-0760(98)00010-7. J Steroid Biochem Mol Biol. 1998. PMID: 9699869 Review.
The motility of several estrogen receptor (ER) positive breast (MCF7, T47D) and ovarian (BG-1, SKOV3, PEO4) cancer cell lines was studied using a modified Boyden chamber assay. We observed, in all cases, estradiol induced inhibition of cancer cell invasion and motility. A …
The motility of several estrogen receptor (ER) positive breast (MCF7, T47D) and ovarian (BG-1, SKOV3, PEO4) cancer cell lines was studied us …
Fatigue and Recovery Time Course After Female Soccer Matches: A Systematic Review And Meta-analysis.
Goulart KNO, Coimbra CC, Campos HO, Drummond LR, Ogando PHM, Brown G, Couto BP, Duffield R, Wanner SP. Goulart KNO, et al. Sports Med Open. 2022 Jun 3;8(1):72. doi: 10.1186/s40798-022-00466-3. Sports Med Open. 2022. PMID: 35657571 Free PMC article.
Small-to-moderate effects were observed for increased cortisol (ES = 0.75) and reduced testosterone/cortisol ratio (ES = -0.47) immediately post-match, while negligible to small effects existed for testosterone (ES = 0.14) and estradiol (ES = 0.34). Large effects were obse …
Small-to-moderate effects were observed for increased cortisol (ES = 0.75) and reduced testosterone/cortisol ratio (ES = -0.47) immediately …
Dexamethasone-suppressible feminizing adrenal adenoma.
Paja M, Díez S, Lucas T, Ojeda A, Salto L, Estrada J. Paja M, et al. Postgrad Med J. 1994 Aug;70(826):584-8. doi: 10.1136/pgmj.70.826.584. Postgrad Med J. 1994. PMID: 7937454 Free PMC article.
A 39 year old man presented with gynaecomastia, loss of libido and high blood pressure. Hormone studies revealed elevated plasma levels of oestradiol and its precursors, which increased in response to adrenocorticotrophic hormone and were reduced to normal levels with dexa …
A 39 year old man presented with gynaecomastia, loss of libido and high blood pressure. Hormone studies revealed elevated plasma levels of …
Estrogen receptors localization and signaling pathways in DU-145 human prostate cancer cells.
Souza DS, Lombardi APG, Vicente CM, Lucas TFG, Erustes AG, Pereira GJS, Porto CS. Souza DS, et al. Mol Cell Endocrinol. 2019 Mar 1;483:11-23. doi: 10.1016/j.mce.2018.12.015. Epub 2019 Jan 17. Mol Cell Endocrinol. 2019. PMID: 30660702
CRM1 inhibitor Leptomycin B reduced drastically the presence of ERalpha and ERbeta in the extranuclear regions and increased in the nuclei, indicating the possible involvement of CRM1 on ERs nuclear-cytoplasmic shuttling. 17beta-estradiol (E2), ERalpha-selective agonist PP …
CRM1 inhibitor Leptomycin B reduced drastically the presence of ERalpha and ERbeta in the extranuclear regions and increased in the nuclei, …
Trans-seasonal activation of the neuroendocrine reproductive axis: Low-temperature winter dormancy modulates gonadotropin-releasing hormone neurons in garter snakes.
Lutterschmidt DI, Lucas AR, Summers AR. Lutterschmidt DI, et al. J Exp Zool A Ecol Integr Physiol. 2022 Jan;337(1):50-64. doi: 10.1002/jez.2506. Epub 2021 Jul 16. J Exp Zool A Ecol Integr Physiol. 2022. PMID: 34270177
Finally, temperature-induced changes in GnRH were sexually dimorphic: neither hibernation temperature nor the duration of winter dormancy significantly modulated GnRH cell number or soma size in females, despite the fact that plasma estradiol and corticosterone increased s …
Finally, temperature-induced changes in GnRH were sexually dimorphic: neither hibernation temperature nor the duration of winter dormancy si …
79 results