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Chemical Chaperones Modulate the Formation of Metabolite Assemblies.
Adsi H, Levkovich SA, Haimov E, Kreiser T, Meli M, Engel H, Simhaev L, Karidi-Heller S, Colombo G, Gazit E, Laor Bar-Yosef D. Adsi H, et al. Among authors: simhaev l. Int J Mol Sci. 2021 Aug 25;22(17):9172. doi: 10.3390/ijms22179172. Int J Mol Sci. 2021. PMID: 34502079 Free PMC article.
Allosteric inhibitors targeting the calmodulin-PIP2 interface of SK4 K+ channels for atrial fibrillation treatment.
Burg S, Shapiro S, Peretz A, Haimov E, Redko B, Yeheskel A, Simhaev L, Engel H, Raveh A, Ben-Bassat A, Murninkas M, Polak R, Haitin Y, Etzion Y, Attali B. Burg S, et al. Among authors: simhaev l. Proc Natl Acad Sci U S A. 2022 Aug 23;119(34):e2202926119. doi: 10.1073/pnas.2202926119. Epub 2022 Aug 15. Proc Natl Acad Sci U S A. 2022. PMID: 35969786 Free PMC article.
An Ancient CFTR Ortholog Informs Molecular Evolution in ABC Transporters.
Cui G, Hong J, Chung-Davidson YW, Infield D, Xu X, Li J, Simhaev L, Khazanov N, Stauffer B, Imhoff B, Cottrill K, Blalock JE, Li W, Senderowitz H, Sorscher E, McCarty NA, Gaggar A. Cui G, et al. Among authors: simhaev l. Dev Cell. 2019 Nov 18;51(4):421-430.e3. doi: 10.1016/j.devcel.2019.09.017. Epub 2019 Oct 31. Dev Cell. 2019. PMID: 31679858 Free PMC article.
2-Hexylthio-β,γ-CH2-ATP is an effective and selective NTPDase2 inhibitor.
Gillerman I, Lecka J, Simhaev L, Munkonda MN, Fausther M, Martín-Satué M, Senderowitz H, Sévigny J, Fischer B. Gillerman I, et al. Among authors: simhaev l. J Med Chem. 2014 Jul 24;57(14):5919-34. doi: 10.1021/jm401933c. Epub 2014 Jul 14. J Med Chem. 2014. PMID: 24972256
16 results