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Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.
Kschonsak YT, Gao X, Miller SE, Hwang S, Marei H, Wu P, Li Y, Ruiz K, Dorighi K, Holokai L, Perampalam P, Tsai WK, Kee YS, Agard NJ, Harris SF, Hannoush RN, de Sousa E Melo F. Kschonsak YT, et al. Among authors: holokai l. Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00421-X. doi: 10.1016/j.chembiol.2023.11.006. Online ahead of print. Cell Chem Biol. 2023. PMID: 38056465
An Organoid-Based Preclinical Model of Human Gastric Cancer.
Steele NG, Chakrabarti J, Wang J, Biesiada J, Holokai L, Chang J, Nowacki LM, Hawkins J, Mahe M, Sundaram N, Shroyer N, Medvedovic M, Helmrath M, Ahmad S, Zavros Y. Steele NG, et al. Among authors: holokai l. Cell Mol Gastroenterol Hepatol. 2019;7(1):161-184. doi: 10.1016/j.jcmgh.2018.09.008. Epub 2018 Sep 20. Cell Mol Gastroenterol Hepatol. 2019. PMID: 30522949 Free PMC article.
Murine- and Human-Derived Autologous Organoid/Immune Cell Co-Cultures as Pre-Clinical Models of Pancreatic Ductal Adenocarcinoma.
Holokai L, Chakrabarti J, Lundy J, Croagh D, Adhikary P, Richards SS, Woodson C, Steele N, Kuester R, Scott A, Khreiss M, Frankel T, Merchant J, Jenkins BJ, Wang J, Shroff RT, Ahmad SA, Zavros Y. Holokai L, et al. Cancers (Basel). 2020 Dec 17;12(12):3816. doi: 10.3390/cancers12123816. Cancers (Basel). 2020. PMID: 33348809 Free PMC article.