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Casein kinase 1 inhibitor avoids TDP-43 pathology propagation in a patient-derived cellular model of amyotrophic lateral sclerosis.
Cuevas EP, Martinez-Gonzalez L, Gordillo C, Tosat-Bitrián C, Pérez de la Lastra C, Sáenz A, Gil C, Palomo V, Martin-Requero Á, Martinez A. Cuevas EP, et al. Among authors: martinez gonzalez l. Neurobiol Dis. 2024 Mar;192:106430. doi: 10.1016/j.nbd.2024.106430. Epub 2024 Feb 5. Neurobiol Dis. 2024. PMID: 38325718 Free article.
TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
Nozal V, Martínez-González L, Gomez-Almeria M, Gonzalo-Consuegra C, Santana P, Chaikuad A, Pérez-Cuevas E, Knapp S, Lietha D, Ramírez D, Petralla S, Monti B, Gil C, Martín-Requero A, Palomo V, de Lago E, Martinez A. Nozal V, et al. Among authors: martinez gonzalez l. J Med Chem. 2022 Jan 27;65(2):1585-1607. doi: 10.1021/acs.jmedchem.1c01942. Epub 2022 Jan 3. J Med Chem. 2022. PMID: 34978799
Insights into real-time chemical processes in a calcium sensor protein-directed dynamic library.
Canal-Martín A, Sastre J, Sánchez-Barrena MJ, Canales A, Baldominos S, Pascual N, Martínez-González L, Molero D, Fernández-Valle ME, Sáez E, Blanco-Gabella P, Gómez-Rubio E, Martín-Santamaría S, Sáiz A, Mansilla A, Cañada FJ, Jiménez-Barbero J, Martínez A, Pérez-Fernández R. Canal-Martín A, et al. Among authors: martinez gonzalez l. Nat Commun. 2019 Jun 26;10(1):2798. doi: 10.1038/s41467-019-10627-w. Nat Commun. 2019. PMID: 31243268 Free PMC article.
23 results