Dietary betaine prevents obesity through gut microbiota-drived microRNA-378a family.
Du J, Zhang P, Luo J, Shen L, Zhang S, Gu H, He J, Wang L, Zhao X, Gan M, Yang L, Niu L, Zhao Y, Tang Q, Tang G, Jiang D, Jiang Y, Li M, Jiang A, Jin L, Ma J, Shuai S, Bai L, Wang J, Zeng B, Wu D, Li X, Zhu L.
Du J, et al. Among authors: jin l.
Gut Microbes. 2021 Jan-Dec;13(1):1-19. doi: 10.1080/19490976.2020.1862612.
Gut Microbes. 2021.
PMID: 33550882
Free PMC article.
However, these beneficial effects are partially abolished by Yin yang (YY1), a common target gene of the miR-378a family. Taken together, our findings demonstrate that betaine can improve obesity and associated MS via the gut microbiota-derived miR-378a/YY1 regulatory axis …
However, these beneficial effects are partially abolished by Yin yang (YY1), a common target gene of the miR-378a family. Taken toget …