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Mixture effects of food-relevant polycyclic aromatic hydrocarbons on the activation of nuclear receptors and gene expression, benzo[a]pyrene metabolite profile and DNA damage in HepaRG cells.
Food Chem Toxicol. 2021 Jan;147:111884. doi: 10.1016/j.fct.2020.111884. Epub 2020 Nov 26.
Food Chem Toxicol. 2021.
PMID: 33249052
Polycyclic Aromatic Hydrocarbons Activate the Aryl Hydrocarbon Receptor and the Constitutive Androstane Receptor to Regulate Xenobiotic Metabolism in Human Liver Cells.
Goedtke L, Sprenger H, Hofmann U, Schmidt FF, Hammer HS, Zanger UM, Poetz O, Seidel A, Braeuning A, Hessel-Pras S.
Goedtke L, et al.
Int J Mol Sci. 2020 Dec 31;22(1):372. doi: 10.3390/ijms22010372.
Int J Mol Sci. 2020.
PMID: 33396476
Free PMC article.
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