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2020 | 3 |
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Page 1
Challenges for Immunotherapy in Multiple Myeloma: Bone Marrow Microenvironment-Mediated Immune Suppression and Immune Resistance.
Cancers (Basel). 2020 Apr 17;12(4):988. doi: 10.3390/cancers12040988.
Cancers (Basel). 2020.
PMID: 32316450
Free PMC article.
Review.
Preclinical evidence for an effective therapeutic activity of FL118, a novel survivin inhibitor, in patients with relapsed/refractory multiple myeloma.
Holthof LC, van der Horst HJ, van Hal-van Veen SE, Ruiter RWJ, Li F, Buijze M, Andersen MN, Yuan H, de Bruijn J, van de Donk NWCJ, Lokhorst HM, Zweegman S, Groen RWJ, Mutis T.
Holthof LC, et al.
Haematologica. 2020 Jan 31;105(2):e80-e83. doi: 10.3324/haematol.2018.213314. Print 2020.
Haematologica. 2020.
PMID: 31123033
Free PMC article.
No abstract available.
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STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes.
Andersen MN, Etzerodt A, Graversen JH, Holthof LC, Moestrup SK, Hokland M, Møller HJ.
Andersen MN, et al. Among authors: holthof lc.
Cancer Immunol Immunother. 2019 Mar;68(3):489-502. doi: 10.1007/s00262-019-02301-3. Epub 2019 Jan 14.
Cancer Immunol Immunother. 2019.
PMID: 30637473
Free PMC article.
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Bone Marrow Mesenchymal Stromal Cells Can Render Multiple Myeloma Cells Resistant to Cytotoxic Machinery of CAR T Cells through Inhibition of Apoptosis.
Holthof LC, van der Schans JJ, Katsarou A, Poels R, Gelderloos AT, Drent E, van Hal-van Veen SE, Li F, Zweegman S, van de Donk NWCJ, Themeli M, Groen RWJ, Mutis T.
Holthof LC, et al.
Clin Cancer Res. 2021 Jul 1;27(13):3793-3803. doi: 10.1158/1078-0432.CCR-20-2188. Epub 2021 Apr 21.
Clin Cancer Res. 2021.
PMID: 33883175
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Preclinical Activity of JNJ-7957, a Novel BCMA×CD3 Bispecific Antibody for the Treatment of Multiple Myeloma, Is Potentiated by Daratumumab.
Frerichs KA, Broekmans MEC, Marin Soto JA, van Kessel B, Heymans MW, Holthof LC, Verkleij CPM, Boominathan R, Vaidya B, Sendecki J, Axel A, Gaudet F, Pillarisetti K, Zweegman S, Adams HC 3rd, Mutis T, van de Donk NWCJ.
Frerichs KA, et al. Among authors: holthof lc.
Clin Cancer Res. 2020 May 1;26(9):2203-2215. doi: 10.1158/1078-0432.CCR-19-2299. Epub 2020 Jan 22.
Clin Cancer Res. 2020.
PMID: 31969333
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Bone Marrow Mesenchymal Stromal Cell-mediated Resistance in Multiple Myeloma Against NK Cells can be Overcome by Introduction of CD38-CAR or TRAIL-variant.
Holthof LC, Stikvoort A, van der Horst HJ, Gelderloos AT, Poels R, Li F, Groen RWJ, Zweegman S, van de Donk NWCJ, O'Dwyer M, Mutis T.
Holthof LC, et al.
Hemasphere. 2021 Apr 21;5(5):e561. doi: 10.1097/HS9.0000000000000561. eCollection 2021 May.
Hemasphere. 2021.
PMID: 33898931
Free PMC article.
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