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2000 1
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164 results

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Page 1
Targeting photodynamic and photothermal therapy to the endoplasmic reticulum enhances immunogenic cancer cell death.
Li W, Yang J, Luo L, Jiang M, Qin B, Yin H, Zhu C, Yuan X, Zhang J, Luo Z, Du Y, Li Q, Lou Y, Qiu Y, You J. Li W, et al. Nat Commun. 2019 Jul 26;10(1):3349. doi: 10.1038/s41467-019-11269-8. Nat Commun. 2019. PMID: 31350406 Free PMC article.
This nanosystem consists of ER-targeting pardaxin (FAL) peptides modified-, indocyanine green (ICG) conjugated- hollow gold nanospheres (FAL-ICG-HAuNS), together with an oxygen-delivering hemoglobin (Hb) liposome (FAL-Hb lipo), designed to reverse hypoxia. Compared with no …
This nanosystem consists of ER-targeting pardaxin (FAL) peptides modified-, indocyanine green (ICG) conjugated- hollow gold nanospheres (FAL …
CPT1A promotes anoikis resistance in esophageal squamous cell carcinoma via redox homeostasis.
Tian T, Lu Y, Lin J, Chen M, Qiu H, Zhu W, Sun H, Huang J, Yang H, Deng W. Tian T, et al. Redox Biol. 2022 Dec;58:102544. doi: 10.1016/j.redox.2022.102544. Epub 2022 Nov 15. Redox Biol. 2022. PMID: 36427397 Free PMC article.
Anoikis resistance was a prominent hallmark of cancer metastasis, and lipo-genic characteristics have been identified as another metabolic alteration during tumorigenesis. ...
Anoikis resistance was a prominent hallmark of cancer metastasis, and lipo-genic characteristics have been identified as another meta …
Liposomes Co-Delivering Curcumin and Colistin to Overcome Colistin Resistance in Bacterial Infections.
Qin C, Tang N, Gan Y, Zhao H, Li Y, Tian GB, Yang YY, Yuan P, Ding X. Qin C, et al. Adv Healthc Mater. 2023 Sep;12(24):e2202903. doi: 10.1002/adhm.202202903. Epub 2023 Aug 11. Adv Healthc Mater. 2023. PMID: 37523195
At the effective antibacterial dose, Lipo-cc does not exhibit any toxicity. The therapeutic efficacy of Lipo-cc is further demonstrated in an intestinal bacterial infection model induced with colistin-resistant Escherichia coli. ...Importantly, unlike colistin, L …
At the effective antibacterial dose, Lipo-cc does not exhibit any toxicity. The therapeutic efficacy of Lipo-cc is further dem …
The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion.
Xia Y, Liu N, Xie X, Bi G, Ba H, Li L, Zhang J, Deng X, Yao Y, Tang Z, Yin B, Wang J, Jiang K, Li Z, Choi Y, Gong F, Cheng X, O'Shea JJ, Chae JJ, Laurence A, Yang XP. Xia Y, et al. Autophagy. 2019 Jun;15(6):960-975. doi: 10.1080/15548627.2019.1569916. Epub 2019 Jan 29. Autophagy. 2019. PMID: 30681394 Free PMC article.
Abbreviations: ACTB/beta-actin: actin, beta; ATG14: autophagy related 14; ATG16L1: autophagy related 16-like 1 (S. cerevisiae); ATP6V0D1/2: ATPase, H+ transporting, lysosomal V0 subunit D1/2; AIM2: absent in melanoma 2; BMDM: bone marrow-derived macrophage; CASP1: caspase 1; CGD: …
Abbreviations: ACTB/beta-actin: actin, beta; ATG14: autophagy related 14; ATG16L1: autophagy related 16-like 1 (S. cerevisiae); ATP6V0D1/2: …
Liposome-anchored mesenchymal stem cells for radiation pneumonia/fibrosis treatment.
Zhou H, Zhang Y, Pei P, Shen W, Yi X, Yang K. Zhou H, et al. Biomaterials. 2023 Sep;300:122202. doi: 10.1016/j.biomaterials.2023.122202. Epub 2023 Jun 14. Biomaterials. 2023. PMID: 37336116
The effectiveness of mesenchymal stem cells (MSCs) on inflammation-related disease is limited and the pharmaceutical preparation that was used to enhance the efficacy of MSCs cannot reach the diseased tissue in large quantities. Herein, antioxidant liposome (Lipo-OPC) is d …
The effectiveness of mesenchymal stem cells (MSCs) on inflammation-related disease is limited and the pharmaceutical preparation that was us …
Deep Tumor Penetration of CRISPR-Cas System for Photothermal-Sensitized Immunotherapy via Probiotics.
Luo W, Zhang Z, Zhou D, Jiang Y, Yang J, He B, Yu H, Song Y. Luo W, et al. Nano Lett. 2023 Sep 13;23(17):8081-8090. doi: 10.1021/acs.nanolett.3c02061. Epub 2023 Aug 24. Nano Lett. 2023. PMID: 37615340
Here, polydopamine-coated Escherichia coli Nissle 1917 (EcN) bearing CRISPR-Cas9 plasmid-loaded liposomes (Lipo-P) are applied for enhanced immunotherapy in deep tumors through activation of innate and adaptive immunity simultaneously. After accumulation in the tumor cente …
Here, polydopamine-coated Escherichia coli Nissle 1917 (EcN) bearing CRISPR-Cas9 plasmid-loaded liposomes (Lipo-P) are applied for en …
Advances in lipo-solubility delivery vehicles for curcumin: bioavailability, precise targeting, possibilities and challenges.
Wen C, Cao L, Yu Z, Liu G, Zhang J, Xu X. Wen C, et al. Crit Rev Food Sci Nutr. 2023 Jul 6:1-20. doi: 10.1080/10408398.2023.2229433. Online ahead of print. Crit Rev Food Sci Nutr. 2023. PMID: 37410019 Review.
SCOPE AND APPROACH: The focus of this review is to emphasize the construction of lipo-solubility delivery vehicles for Cur, including emulsion, nanoliposome and solid liposome. ...Further, the deficiencies and prospects of Cur encapsulated in vehicles for precise nutrition …
SCOPE AND APPROACH: The focus of this review is to emphasize the construction of lipo-solubility delivery vehicles for Cur, including …
Lipo-PGE1 suppresses collagen production in human dermal fibroblasts via the ERK/Ets-1 signaling pathway.
Yang Y, Kim HJ, Woo KJ, Cho D, Bang SI. Yang Y, et al. PLoS One. 2017 Jun 23;12(6):e0179614. doi: 10.1371/journal.pone.0179614. eCollection 2017. PLoS One. 2017. PMID: 28644845 Free PMC article.
No published study has characterized the role of Lipo-PGE1 in collagen regulation in HDFs. Here, we investigated the cellular signaling mechanism by which Lipo-PGE1 regulates collagen in HDFs. ...Moreover, Lipo-PGE1 directly induced the phosphorylation of ERK …
No published study has characterized the role of Lipo-PGE1 in collagen regulation in HDFs. Here, we investigated the cellular signali …
Silencing Gene-Engineered Injectable Hydrogel Microsphere for Regulation of Extracellular Matrix Metabolism Balance.
Chang H, Cai F, Zhang Y, Jiang M, Yang X, Qi J, Wang L, Deng L, Cui W, Liu X. Chang H, et al. Small Methods. 2022 Apr;6(4):e2101201. doi: 10.1002/smtd.202101201. Epub 2022 Jan 6. Small Methods. 2022. PMID: 34994105
In the rat IVD nutrient-restricted model, local injection of psh-circSTC2-lipo@MS promotes ECM synthesis and restored NP tissue after 8 weeks. In summary, this study confirms that psh-circSTC2-lipo@MS as a safe and controllable targeted gene delivery system has grea …
In the rat IVD nutrient-restricted model, local injection of psh-circSTC2-lipo@MS promotes ECM synthesis and restored NP tissue after …
Briarane-Related Diterpenoids from Octocoral Briareum stechei.
Huynh TH, Neoh CA, Tsai YC, Yao ZK, Zheng LG, Huang PC, Wen ZH, Chen JJ, Wu YJ, Sung PJ. Huynh TH, et al. Molecules. 2021 Nov 13;26(22):6861. doi: 10.3390/molecules26226861. Molecules. 2021. PMID: 34833953 Free PMC article.
In addition, briarane 1 demonstrated anti-inflammatory activity in lipo-polysaccharide-induced RAW 264.7 mouse macrophage cells by suppressing the expression of inducible nitric oxide synthase (iNOS) protein....
In addition, briarane 1 demonstrated anti-inflammatory activity in lipo-polysaccharide-induced RAW 264.7 mouse macrophage cells by su …
164 results