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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1958 2
1967 3
1968 2
1969 4
1970 8
1971 7
1972 4
1973 8
1974 19
1975 84
1976 76
1977 63
1978 71
1979 95
1980 118
1981 124
1982 147
1983 192
1984 189
1985 207
1986 209
1987 208
1988 223
1989 271
1990 299
1991 303
1992 302
1993 336
1994 379
1995 376
1996 454
1997 416
1998 508
1999 480
2000 547
2001 616
2002 631
2003 764
2004 921
2005 1040
2006 1054
2007 1109
2008 1290
2009 1539
2010 1627
2011 1770
2012 1980
2013 2125
2014 2159
2015 2211
2016 1596
2017 1419
2018 1765
2019 1842
2020 1908
2021 1818
2022 1031
2023 774
2024 197

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36,435 results

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Page 1
Novel Approaches to the Treatment of Chronic Graft-Versus-Host Disease.
Zeiser R. Zeiser R. J Clin Oncol. 2023 Apr 1;41(10):1820-1824. doi: 10.1200/JCO.22.02256. Epub 2023 Feb 17. J Clin Oncol. 2023. PMID: 36800551 Review.
The current standard first-line cGVHD therapy is glucocorticoids (GCs) which have major side effects. So far, all attempts to improve response to first-line GC therapy of cGVHD by adding other agents, such as mycophenolate mofetil, or cyclosporine A have not improve …
The current standard first-line cGVHD therapy is glucocorticoids (GCs) which have major side effects. So far, all attempts to improve …
Bioprocessing of Recombinant CHO-K1, CHO-DG44, and CHO-S: CHO Expression Hosts Favor Either mAb Production or Biomass Synthesis.
Reinhart D, Damjanovic L, Kaisermayer C, Sommeregger W, Gili A, Gasselhuber B, Castan A, Mayrhofer P, Grünwald-Gruber C, Kunert R. Reinhart D, et al. Biotechnol J. 2019 Mar;14(3):e1700686. doi: 10.1002/biot.201700686. Epub 2018 Jun 11. Biotechnol J. 2019. PMID: 29701329
Further, two different cell culture media are used to investigate their effects. The authors find CHO cell line-specific preferences for mAb production or biomass synthesis that are determined by the host cell line. Additionally, quality attributes of the exp …
Further, two different cell culture media are used to investigate their effects. The authors find CHO cell line-specific preferences …
Understanding virus-host interactions in tissues.
Speranza E. Speranza E. Nat Microbiol. 2023 Aug;8(8):1397-1407. doi: 10.1038/s41564-023-01434-7. Epub 2023 Jul 24. Nat Microbiol. 2023. PMID: 37488255 Review.
These factors affect how the host responds to the virus and form the basis of the protective response. To understand virus infection, tools are needed that can profile the tissue environment. This Review highlights methods to study virus-host interactions in the inf …
These factors affect how the host responds to the virus and form the basis of the protective response. To understand virus infection, …
Great exaptations.
Burns KH, Boeke JD. Burns KH, et al. J Biol. 2008;7(2):5. doi: 10.1186/jbiol66. J Biol. 2008. PMID: 18279541 Free PMC article. Review.
Long interspersed nuclear elements (LINEs) are among the most successful parasitic genetic sequences in higher organisms. Recent work has discovered many instances of LINE incorporation into exons, reminding us of the hazards they pose to genes in their vicinity as well as …
Long interspersed nuclear elements (LINEs) are among the most successful parasitic genetic sequences in higher organisms. Recent work has di …
Beyond Viral Interferon Regulatory Factors: Immune Evasion Strategies.
Myoung J, Lee SA, Lee HR. Myoung J, et al. J Microbiol Biotechnol. 2019 Dec 28;29(12):1873-1881. doi: 10.4014/jmb.1910.10004. J Microbiol Biotechnol. 2019. PMID: 31650769 Free article. Review.
The innate immune response serves as a first-line-of-defense mechanism for a host against viral infection. Viruses must therefore subvert this anti-viral response in order to establish an efficient life cycle. In line with this fact, Kaposi's sarcoma-a …
The innate immune response serves as a first-line-of-defense mechanism for a host against viral infection. Viruses must theref …
Second-line therapy for patients with steroid-refractory aGVHD: systematic review and meta-analysis of randomized controlled trials.
Luo C, Huang X, Wei L, Wu G, Huang Y, Ding Y, Huang Z, Chen J, Li X, Zou Y, Xu S. Luo C, et al. Front Immunol. 2023 Jun 20;14:1211171. doi: 10.3389/fimmu.2023.1211171. eCollection 2023. Front Immunol. 2023. PMID: 37409129 Free PMC article.
OBJECTIVE: Steroids-refractory (SR) acute graft-versus-host disease (aGVHD) is a life-threatening condition in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT), but the optimal second-line therapy still has not been established. ... …
OBJECTIVE: Steroids-refractory (SR) acute graft-versus-host disease (aGVHD) is a life-threatening condition in patients undergoing al …
Unveiling the Sugary Secrets of Plasmodium Parasites.
Goerdeler F, Seeberger PH, Moscovitz O. Goerdeler F, et al. Front Microbiol. 2021 Jul 16;12:712538. doi: 10.3389/fmicb.2021.712538. eCollection 2021. Front Microbiol. 2021. PMID: 34335547 Free PMC article. Review.
In contrast, complex glycosylphosphatidylinositol (GPI) glycolipids are highly abundant on the parasite's cell membrane and are essential for its survival. Moreover, the parasites express lectins that bind and exploit the host cell surface glycans for different aspe …
In contrast, complex glycosylphosphatidylinositol (GPI) glycolipids are highly abundant on the parasite's cell membrane and are essen …
Streptococcus mitis: walking the line between commensalism and pathogenesis.
Mitchell J. Mitchell J. Mol Oral Microbiol. 2011 Apr;26(2):89-98. doi: 10.1111/j.2041-1014.2010.00601.x. Epub 2011 Jan 18. Mol Oral Microbiol. 2011. PMID: 21375700 Review.
The recent publication of a complete genome sequence for S. mitis strain B6 will allow researchers to thoroughly investigate which genes are involved in S. mitis host colonization and pathogenesis. Moreover, it will help to give insight into where S. m …
The recent publication of a complete genome sequence for S. mitis strain B6 will allow researchers to thoroughly investigate which ge …
Human TRIM5alpha senses and restricts LINE-1 elements.
Volkmann B, Wittmann S, Lagisquet J, Deutschmann J, Eissmann K, Ross JJ, Biesinger B, Gramberg T. Volkmann B, et al. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):17965-17976. doi: 10.1073/pnas.1922366117. Epub 2020 Jul 10. Proc Natl Acad Sci U S A. 2020. PMID: 32651277 Free PMC article.
In line with its postulated role as pattern recognition receptor, we show that TRIM5alpha also induces innate immune signaling upon interaction with LINE-1 ribonucleoprotein complexes. The signaling events activate the transcription factors AP-1 and NF-kappaB, leadi …
In line with its postulated role as pattern recognition receptor, we show that TRIM5alpha also induces innate immune signaling upon i …
Campylobacter-host cell interactions.
Wooldridge KG, Ketley JM. Wooldridge KG, et al. Trends Microbiol. 1997 Mar;5(3):96-102. doi: 10.1016/S0966-842X(97)01004-4. Trends Microbiol. 1997. PMID: 9080607 Review.
Their ability to adhere to human epithelial cells is ubiquitous and their propensity to invade cells is also well documented and requires motility and de novo protein synthesis, as well as several host factors. The molecular basis of the interaction between campylobacters …
Their ability to adhere to human epithelial cells is ubiquitous and their propensity to invade cells is also well documented and requires mo …
36,435 results
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