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A CRISP(e)R view on kidney organoids allows generation of an induced pluripotent stem cell-derived kidney model for drug discovery.
Kidney Int. 2018 Dec;94(6):1099-1110. doi: 10.1016/j.kint.2018.05.003. Epub 2018 Jul 31.
Kidney Int. 2018.
PMID: 30072040
Free article.
AZD8797 is an allosteric non-competitive modulator of the human CX3CR1 receptor.
Cederblad L, Rosengren B, Ryberg E, Hermansson NO.
Cederblad L, et al.
Biochem J. 2016 Mar 1;473(5):641-9. doi: 10.1042/BJ20150520. Epub 2015 Dec 11.
Biochem J. 2016.
PMID: 26656484
Free PMC article.
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The structures of salt-inducible kinase 3 in complex with inhibitors reveal determinants for binding and selectivity.
Öster L, Castaldo M, de Vries E, Edfeldt F, Pemberton N, Gordon E, Cederblad L, Käck H.
Öster L, et al. Among authors: cederblad l.
J Biol Chem. 2024 May;300(5):107201. doi: 10.1016/j.jbc.2024.107201. Epub 2024 Mar 18.
J Biol Chem. 2024.
PMID: 38508313
Free PMC article.
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Renal Endothelial Single-Cell Transcriptomics Reveals Spatiotemporal Regulation and Divergent Roles of Differential Gene Transcription and Alternative Splicing in Murine Diabetic Nephropathy.
Zhou AX, Jeansson M, He L, Wigge L, Tonelius P, Tati R, Cederblad L, Muhl L, Uhrbom M, Liu J, Björnson Granqvist A, Lerman LO, Betsholtz C, Hansen PBL.
Zhou AX, et al. Among authors: cederblad l.
Int J Mol Sci. 2024 Apr 13;25(8):4320. doi: 10.3390/ijms25084320.
Int J Mol Sci. 2024.
PMID: 38673910
Free PMC article.
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