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Phase I/II study of G3139 (Bcl-2 antisense oligonucleotide) in combination with doxorubicin and docetaxel in breast cancer.
Moulder SL, Symmans WF, Booser DJ, Madden TL, Lipsanen C, Yuan L, Brewster AM, Cristofanilli M, Hunt KK, Buchholz TA, Zwiebel J, Valero V, Hortobagyi GN, Esteva FJ. Moulder SL, et al. Among authors: yuan l. Clin Cancer Res. 2008 Dec 1;14(23):7909-16. doi: 10.1158/1078-0432.CCR-08-1104. Clin Cancer Res. 2008. PMID: 19047121 Free PMC article. Clinical Trial.
PEA-15 inhibits tumorigenesis in an MDA-MB-468 triple-negative breast cancer xenograft model through increased cytoplasmic localization of activated extracellular signal-regulated kinase.
Bartholomeusz C, Gonzalez-Angulo AM, Kazansky A, Krishnamurthy S, Liu P, Yuan LX, Yamasaki F, Liu S, Hayashi N, Zhang D, Esteva FJ, Hortobagyi GN, Ueno NT. Bartholomeusz C, et al. Among authors: yuan lx. Clin Cancer Res. 2010 Mar 15;16(6):1802-11. doi: 10.1158/1078-0432.CCR-09-1456. Epub 2010 Mar 9. Clin Cancer Res. 2010. PMID: 20215547