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Year Number of Results
2002 6
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Page 1
Showing results for li mei tu
Search for Limei Tu instead (1 results)
Estimated Burden of Stroke in China in 2020.
Tu WJ, Zhao Z, Yin P, Cao L, Zeng J, Chen H, Fan D, Fang Q, Gao P, Gu Y, Tan G, Han J, He L, Hu B, Hua Y, Kang D, Li H, Liu J, Liu Y, Lou M, Luo B, Pan S, Peng B, Ren L, Wang L, Wu J, Xu Y, Xu Y, Yang Y, Zhang M, Zhang S, Zhu L, Zhu Y, Li Z, Chu L, An X, Wang L, Yin M, Li M, Yin L, Yan W, Li C, Tang J, Zhou M, Wang L. Tu WJ, et al. Among authors: li m. JAMA Netw Open. 2023 Mar 1;6(3):e231455. doi: 10.1001/jamanetworkopen.2023.1455. JAMA Netw Open. 2023. PMID: 36862407 Free PMC article.
Thymidine kinase 1 drives hepatocellular carcinoma in enzyme-dependent and -independent manners.
Li Q, Zhang L, Yang Q, Li M, Pan X, Xu J, Zhong C, Yao F, Zhang R, Zhou S, Dai X, Shi X, Dai Y, Xu J, Cheng X, Xiao W, She Z, Wang K, Qian X, Pu L, Zhang P, Wang X. Li Q, et al. Among authors: li m. Cell Metab. 2023 Jun 6;35(6):912-927.e7. doi: 10.1016/j.cmet.2023.03.017. Epub 2023 Apr 17. Cell Metab. 2023. PMID: 37071992
Mechanistically, TK1 directly binds PRMT1 and stabilizes it by interrupting its interactions with tripartite-motif-containing 48 (TRIM48), which inhibits its ubiquitination-mediated degradation. Subsequently, we validate the therapeutic capacity of hepatic TK1 knockdown in …
Mechanistically, TK1 directly binds PRMT1 and stabilizes it by interrupting its interactions with tripartite-motif-containing 48 (TRIM48), w …
A Logic-Based Diagnostic and Therapeutic Hydrogel with Multistimuli Responsiveness to Orchestrate Diabetic Bone Regeneration.
Li D, Chen K, Tang H, Hu S, Xin L, Jing X, He Q, Wang S, Song J, Mei L, Cannon RD, Ji P, Wang H, Chen T. Li D, et al. Among authors: mei l. Adv Mater. 2022 Mar;34(11):e2108430. doi: 10.1002/adma.202108430. Epub 2022 Feb 3. Adv Mater. 2022. PMID: 34921569
It exhibits a "diagnostic" logic to interpret pathological cues (glucose fluctuation, ROS, MMPs) and determines when to release drug in a diabetic microenvironment and a therapeutic logic to program different cargo release to match immune-osteo cascade for better tissue re …
It exhibits a "diagnostic" logic to interpret pathological cues (glucose fluctuation, ROS, MMPs) and determines when to release drug in a di …
Phosphorylation of USP29 by CDK1 Governs TWIST1 Stability and Oncogenic Functions.
Guan T, Li M, Song Y, Chen J, Tang J, Zhang C, Wen Y, Yang X, Huang L, Zhu Y, Wang H, Ding K, Zheng J, Zhang H, Liu T. Guan T, et al. Among authors: li m. Adv Sci (Weinh). 2023 Apr;10(11):e2205873. doi: 10.1002/advs.202205873. Epub 2023 Feb 13. Adv Sci (Weinh). 2023. PMID: 36782089 Free PMC article.
Taken together, the findings reveal a previously unrecognized tumor-promoting function and clinical significance of the CDK1-USP29 axis through stabilizing TWIST1 and provide the preclinical evidence that targeting this axis is an appealing therapeutic strategy to conquer …
Taken together, the findings reveal a previously unrecognized tumor-promoting function and clinical significance of the CDK1-USP29 axis thro …
Inflammatory cytokine-regulated tRNA-derived fragment tRF-21 suppresses pancreatic ductal adenocarcinoma progression.
Pan L, Huang X, Liu ZX, Ye Y, Li R, Zhang J, Wu G, Bai R, Zhuang L, Wei L, Li M, Zheng Y, Su J, Deng J, Deng S, Zeng L, Zhang S, Wu C, Che X, Wang C, Chen R, Lin D, Zheng J. Pan L, et al. Among authors: li m. J Clin Invest. 2021 Nov 15;131(22):e148130. doi: 10.1172/JCI148130. J Clin Invest. 2021. PMID: 34779408 Free PMC article.
These results demonstrate that tRF-21 has a tumor-suppressive effect and is a potential therapeutic agent for PDAC....
These results demonstrate that tRF-21 has a tumor-suppressive effect and is a potential therapeutic agent for PDAC....
NSUN2-mediated RNA 5-methylcytosine promotes esophageal squamous cell carcinoma progression via LIN28B-dependent GRB2 mRNA stabilization.
Su J, Wu G, Ye Y, Zhang J, Zeng L, Huang X, Zheng Y, Bai R, Zhuang L, Li M, Pan L, Deng J, Li R, Deng S, Zhang S, Zuo Z, Liu Z, Lin J, Lin D, Zheng J. Su J, et al. Among authors: li m. Oncogene. 2021 Sep;40(39):5814-5828. doi: 10.1038/s41388-021-01978-0. Epub 2021 Aug 3. Oncogene. 2021. PMID: 34345012 Free PMC article.
These results demonstrate that NSUN2 enhances the initiation and progression of ESCC via m(5)C-LIN28B dependent stabilization of GRB2 transcript, providing a promising epitranscriptomic-targeted therapeutic strategy for ESCC....
These results demonstrate that NSUN2 enhances the initiation and progression of ESCC via m(5)C-LIN28B dependent stabilization of GRB2 transc …
A Probody T Cell-Engaging Bispecific Antibody Targeting EGFR and CD3 Inhibits Colon Cancer Growth with Limited Toxicity.
Boustany LM, LaPorte SL, Wong L, White C, Vinod V, Shen J, Yu W, Koditek D, Winter MB, Moore SJ, Mei L, Diep L, Huang Y, Liu S, Vasiljeva O, West J, Richardson J, Irving B, Belvin M, Kavanaugh WM. Boustany LM, et al. Among authors: mei l. Cancer Res. 2022 Nov 15;82(22):4288-4298. doi: 10.1158/0008-5472.CAN-21-2483. Cancer Res. 2022. PMID: 36112781 Free PMC article.
SIGNIFICANCE: A conditionally active EGFR-CD3 T cell-engaging Probody therapeutic expands the safety window of bispecific antibodies while maintaining efficacy in preclinical solid tumor settings....
SIGNIFICANCE: A conditionally active EGFR-CD3 T cell-engaging Probody therapeutic expands the safety window of bispecific antibodies …
CSTF2 mediated mRNA N6-methyladenosine modification drives pancreatic ductal adenocarcinoma m6A subtypes.
Zheng Y, Li X, Deng S, Zhao H, Ye Y, Zhang S, Huang X, Bai R, Zhuang L, Zhou Q, Li M, Su J, Li R, Bao X, Zeng L, Chen R, Zheng J, Lin D, He C, Zhang J, Zuo Z. Zheng Y, et al. Among authors: li m. Nat Commun. 2023 Oct 10;14(1):6334. doi: 10.1038/s41467-023-41861-y. Nat Commun. 2023. PMID: 37816727 Free PMC article.
These results provide a promising PDAC subtyping strategy and potential therapeutic targets for precision medicine of PDAC....
These results provide a promising PDAC subtyping strategy and potential therapeutic targets for precision medicine of PDAC....
498 results