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694 results

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The following term was not found in PubMed: Likane
Page 1
Canagliflozin mitigates ferroptosis and improves myocardial oxidative stress in mice with diabetic cardiomyopathy.
Du S, Shi H, Xiong L, Wang P, Shi Y. Du S, et al. Front Endocrinol (Lausanne). 2022 Oct 14;13:1011669. doi: 10.3389/fendo.2022.1011669. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36313744 Free PMC article.
Canagliflozin (Cana), an anti-diabetes drug belongs to sodium-glucose cotransporter 2 inhibitor, is gaining interest because of its extra cardiovascular benefits. ...As a key inducer of ferroptosis, the deposition of total iron and Fe(2+) can be inhibited by Cana bo …
Canagliflozin (Cana), an anti-diabetes drug belongs to sodium-glucose cotransporter 2 inhibitor, is gaining interest because of its e …
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Chen A, Lan Z, Li L, Xie L, Liu X, Yang X, Wang S, Liang Q, Dong Q, Feng L, Li Y, Ye Y, Fu M, Lu L, Yan J. Chen A, et al. Cardiovasc Res. 2023 Oct 24;119(13):2368-2381. doi: 10.1093/cvr/cvad119. Cardiovasc Res. 2023. PMID: 37523743
However, the effect of CANA on VC remains unknown. In this study, we hypothesize that CANA protects against VC. ...Moreover, CANA alleviated the calcification of rat and human arterial rings. ...
However, the effect of CANA on VC remains unknown. In this study, we hypothesize that CANA protects against VC. ...Moreover, …
Canagliflozin combined with metformin versus metformin monotherapy for endocrine and metabolic profiles in overweight and obese women with polycystic ovary syndrome: A single-center, open-labeled prospective randomized controlled trial.
Zhang J, Xing C, Cheng X, He B. Zhang J, et al. Front Endocrinol (Lausanne). 2022 Sep 6;13:1003238. doi: 10.3389/fendo.2022.1003238. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36147577 Free PMC article. Clinical Trial.
OBJECTIVES: Canagliflozin (CANA), a kind of sodium-glucose cotransporter-2 (SGLT-2) inhibition, study in which the role of CANA monotherapy in polycystic ovary syndrome (PCOS) has been investigated, and it could become a novel option in the PCOS treatment. ...METHOD …
OBJECTIVES: Canagliflozin (CANA), a kind of sodium-glucose cotransporter-2 (SGLT-2) inhibition, study in which the role of CANA …
The diabetes medication canagliflozin promotes mitochondrial remodelling of adipocyte via the AMPK-Sirt1-Pgc-1α signalling pathway.
Yang X, Liu Q, Li Y, Tang Q, Wu T, Chen L, Pu S, Zhao Y, Zhang G, Huang C, Zhang J, Zhang Z, Huang Y, Zou M, Shi X, Jiang W, Wang R, He J. Yang X, et al. Adipocyte. 2020 Dec;9(1):484-494. doi: 10.1080/21623945.2020.1807850. Adipocyte. 2020. PMID: 32835596 Free PMC article.
Cana treatment also reduces body weight. However, it remains unclear whether Cana could directly work on adipose tissue. In the present study, the pharmacological effects of Cana and the associated mechanism were investigated in adipocytes and mice. ...
Cana treatment also reduces body weight. However, it remains unclear whether Cana could directly work on adipose tissue. In th …
Canagliflozin reduces chemoresistance in hepatocellular carcinoma through PKM2-c-Myc complex-mediated glutamine starvation.
Zeng Y, Jiang H, Zhang X, Xu J, Wu X, Xu Q, Cai W, Ying H, Zhou R, Ding Y, Ying K, Song X, Chen Z, Zeng L, Zhao L, Yu F. Zeng Y, et al. Free Radic Biol Med. 2023 Nov 1;208:571-586. doi: 10.1016/j.freeradbiomed.2023.09.006. Epub 2023 Sep 9. Free Radic Biol Med. 2023. PMID: 37696420
However, its use is limits as a monotherapy due to drug resistance, and the underlying mechanism remains unclear. To solve this problem, we tried using canagliflozin (CANA), a clinical drug for diabetes, to reduce chemoresistance to CPT, and the result showed that CANA …
However, its use is limits as a monotherapy due to drug resistance, and the underlying mechanism remains unclear. To solve this problem, we …
Factores asociados con el cambio en la inseguridad alimentaria en México: Ensanut 2012 y 2018-19.
Shamah-Levy T, Méndez-Gómez Humarán I, Mundo-Rosas V, Rodríguez-Ramírez S, Gaona-Pineda EB. Shamah-Levy T, et al. Salud Publica Mex. 2021 May 3;63(3 May-Jun):350-358. doi: 10.21149/12145. Salud Publica Mex. 2021. PMID: 34098611 Spanish.
Material y metodos. Se obtuvo informacion de la Escala Latinoameri-cana y Caribena de Seguridad Alimentaria en ambas encuestas. Mediante modelos de regresion logistica ordinal se evaluo la contribucion de ser beneficiario de programas sociales y otras variables sociodemogr …
Material y metodos. Se obtuvo informacion de la Escala Latinoameri-cana y Caribena de Seguridad Alimentaria en ambas encuestas. Media …
Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice.
Yildirim G, Bergamo ETP, Poudel SB, Ruff RR, Dixit M, Hu B, Mijares DQ, Witek L, Chlebek C, Harrison DE, Strong R, Miller RA, Ladiges W, Bromage TG, Rosen CJ, Yakar S. Yildirim G, et al. Geroscience. 2023 Jun;45(3):1933-1951. doi: 10.1007/s11357-023-00803-8. Epub 2023 May 11. Geroscience. 2023. PMID: 37166526 Free PMC article.
Micro-computed tomography (micro-CT) revealed that CANA treatment caused significant thinning of the femur mid-diaphyseal cortex in both male and female mice, did not affect trabecular bone architecture in the distal femur or the lumbar vertebra-5 in male mice, but was ass …
Micro-computed tomography (micro-CT) revealed that CANA treatment caused significant thinning of the femur mid-diaphyseal cortex in b …
Canagliflozin ameliorates the development of NAFLD by preventing NLRP3-mediated pyroptosis through FGF21-ERK1/2 pathway.
Huang S, Wu B, He Y, Qiu R, Yang T, Wang S, Lei Y, Li H, Zheng F. Huang S, et al. Hepatol Commun. 2023 Feb 9;7(3):e0045. doi: 10.1097/HC9.0000000000000045. eCollection 2023 Mar 1. Hepatol Commun. 2023. PMID: 36757426 Free PMC article.
Furthermore, inflammation and fibrosis genes decreased in the livers of CANA-treated ob/ob and diabetic mice mice. FGF21 and its downstream ERK1/2/AMPK signaling decreased, whereas NLRP3-mediated pyroptosis increased in the livers of the ob/ob and diabetic mice mice, which …
Furthermore, inflammation and fibrosis genes decreased in the livers of CANA-treated ob/ob and diabetic mice mice. FGF21 and its down …
Thermoluminescence study of CaNa(2) (SO(4) )(2) phosphor doped with Eu(3+) and synthesized by combustion method.
Bargat SR, Parauha YR, Mishra GC, Dhoble SJ. Bargat SR, et al. Luminescence. 2021 Dec;36(8):1862-1868. doi: 10.1002/bio.3940. Epub 2020 Oct 1. Luminescence. 2021. PMID: 32841478
In the present study, the thermoluminescence (TL) properties of an Eu(3+) -doped CaNa(2) (SO(4) )(2) phosphor were studied. The Eu(3+) -doped CaNa(2) (SO(4) )(2) phosphor was synthesized using the combustion method. ...Each characteristic of these outcomes demonstra …
In the present study, the thermoluminescence (TL) properties of an Eu(3+) -doped CaNa(2) (SO(4) )(2) phosphor were studied. The Eu(3+ …
694 results