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Did you mean leibo ai (1 results)?
Randomized, Single-Blind, Multicenter Phase II Study of Two Doses of Imetelstat in Relapsed or Refractory Myelofibrosis.
Mascarenhas J, Komrokji RS, Palandri F, Martino B, Niederwieser D, Reiter A, Scott BL, Baer MR, Hoffman R, Odenike O, Vannucchi AM, Bussolari J, Zhu E, Rose E, Sherman L, Dougherty S, Sun L, Huang F, Wan Y, Feller FM, Rizo A, Kiladjian JJ. Mascarenhas J, et al. J Clin Oncol. 2021 Sep 10;39(26):2881-2892. doi: 10.1200/JCO.20.02864. Epub 2021 Jun 17. J Clin Oncol. 2021. PMID: 34138638 Clinical Trial.
PURPOSE: Patients with myelofibrosis who are relapsed or refractory (R/R) to Janus-associated kinase inhibitors (JAKis) have poor clinical outcomes including dismal overall survival (OS) that ranges between 13 and 16 months. ...
PURPOSE: Patients with myelofibrosis who are relapsed or refractory (R/R) to Janus-associated kinase inhibitors (JAKis) have poor cli …
Design, synthesis and evaluation of d-amino acid-containing peptidomimetics targeting the polo-box domain of polo-like kinase 1.
Li Z, Zhang Z, Chen Y, Tang S, Lin T, Huang J, Li B, Jiang C. Li Z, et al. Bioorg Chem. 2019 Apr;85:534-540. doi: 10.1016/j.bioorg.2019.02.022. Epub 2019 Feb 11. Bioorg Chem. 2019. PMID: 30807896
A series of d-amino acid-containing peptidomimetics were designed, synthesized as novel polo-like kinase 1 (Plk1) polo-box domain (PBD) inhibitors based on the reported peptide Plk1 PBD inhibitor. Their inhibitory activity to Plk1, Plk2, and Plk3 PBD were evaluated using o …
A series of d-amino acid-containing peptidomimetics were designed, synthesized as novel polo-like kinase 1 (Plk1) polo-box domain (PBD) i …
Design, synthesis and biological activity evaluation of novel 4-((1-cyclopropyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl) oxy) pyridine-2-yl) amino derivatives as potent transforming growth factor-beta (TGF-beta) type I receptor inhibitors.
Tan B, Zhang X, Quan X, Zheng G, Li X, Zhao L, Li W, Li B. Tan B, et al. Bioorg Med Chem Lett. 2020 Aug 15;30(16):127339. doi: 10.1016/j.bmcl.2020.127339. Epub 2020 Jun 10. Bioorg Med Chem Lett. 2020. PMID: 32631540
TGF-beta type I receptor (also known as activin-like kinase 5 or ALK5) plays a critical role in the progression of fibrotic diseases and tumor invasiveness and metastasis, as well. The development of small inhibitors targeting ALK5 has been validated as a potential therape …
TGF-beta type I receptor (also known as activin-like kinase 5 or ALK5) plays a critical role in the progression of fibrotic diseases and tum …
[Variation and regularity of volatile oil constituents in fruits of national medicine Cinnamomum migao].
Zhou T, Yang Z, Jiang W, Ai Q, Guo P. Zhou T, et al. Zhongguo Zhong Yao Za Zhi. 2010 Apr;35(7):852-6. doi: 10.4268/cjcmm20100710. Zhongguo Zhong Yao Za Zhi. 2010. PMID: 20575384 Chinese.
The type of eucalyptol, eucalyptol -sabinene and eucalyptol -alpha-terpineol were cultivated in Ceheng and Libo regions, Guizhou province. CONCLUSION: Combined with the geographical distribution, It is indicated that the volatile oil compositions in fruit of C. migao may h …
The type of eucalyptol, eucalyptol -sabinene and eucalyptol -alpha-terpineol were cultivated in Ceheng and Libo regions, Guizhou prov …