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Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects.
Miller IS, Khan S, Shiels LP, Das S, O' Farrell AC, Connor K, Lafferty A, Moran B, Isella C, Loadman P, Conroy E, Cohrs S, Schibli R, Kerbel RS, Gallagher WM, Marangoni E, Bennett K, O' Connor DP, Dwyer RM, Byrne AT. Miller IS, et al. Among authors: shiels lp. Cancer Med. 2022 Oct;11(20):3820-3836. doi: 10.1002/cam4.4756. Epub 2022 Apr 17. Cancer Med. 2022. PMID: 35434898 Free PMC article.
Targeting the RhoGEF βPIX/COOL-1 in Glioblastoma: Proof of Concept Studies.
Connor K, Murray DW, Jarzabek MA, Tran NL, White K, Dicker P, Sweeney KJ, O'Halloran PJ, MacCarthy B, Shiels LP, Lodi F, Lambrechts D, Sarkaria JN, Schiffelers RM, Symons M, Byrne AT. Connor K, et al. Among authors: shiels lp. Cancers (Basel). 2020 Nov 26;12(12):3531. doi: 10.3390/cancers12123531. Cancers (Basel). 2020. PMID: 33256106 Free PMC article.
When RON MET TAM in Mesothelioma: All Druggable for One, and One Drug for All?
Baird AM, Easty D, Jarzabek M, Shiels L, Soltermann A, Klebe S, Raeppel S, MacDonagh L, Wu C, Griggs K, Kirschner MB, Stanfill B, Nonaka D, Goparaju CM, Murer B, Fennell DA, O'Donnell DM, Barr MP, Mutti L, Reid G, Finn S, Cuffe S, Pass HI, Opitz I, Byrne AT, O'Byrne KJ, Gray SG. Baird AM, et al. Among authors: shiels l. Front Endocrinol (Lausanne). 2019 Feb 26;10:89. doi: 10.3389/fendo.2019.00089. eCollection 2019. Front Endocrinol (Lausanne). 2019. PMID: 30863365 Free PMC article.
A clinically relevant computed tomography (CT) radiomics strategy for intracranial rodent brain tumour monitoring.
Connor K, Conroy E, White K, Shiels LP, Keek S, Ibrahim A, Gallagher WM, Sweeney KJ, Clerkin J, O'Brien D, Cryan JB, O'Halloran PJ, Heffernan J, Brett F, Lambin P, Woodruff HC, Byrne AT. Connor K, et al. Among authors: shiels lp. Sci Rep. 2024 Feb 1;14(1):2720. doi: 10.1038/s41598-024-52960-1. Sci Rep. 2024. PMID: 38302657 Free PMC article.
Implementing Systems Modelling and Molecular Imaging to Predict the Efficacy of BCL-2 Inhibition in Colorectal Cancer Patient-Derived Xenograft Models.
O'Farrell AC, Jarzabek MA, Lindner AU, Carberry S, Conroy E, Miller IS, Connor K, Shiels L, Zanella ER, Lucantoni F, Lafferty A, White K, Meyer Villamandos MM, Dicker P, Gallagher WM, Keek SA, Sanduleanu S, Lambin P, Woodruff HC, Bertotti A, Trusolino L, Byrne AT, Prehn JHM. O'Farrell AC, et al. Among authors: shiels l. Cancers (Basel). 2020 Oct 14;12(10):2978. doi: 10.3390/cancers12102978. Cancers (Basel). 2020. PMID: 33066609 Free PMC article.
A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate.
O'Farrell AC, Evans R, Silvola JM, Miller IS, Conroy E, Hector S, Cary M, Murray DW, Jarzabek MA, Maratha A, Alamanou M, Udupi GM, Shiels L, Pallaud C, Saraste A, Liljenbäck H, Jauhiainen M, Oikonen V, Ducret A, Cutler P, McAuliffe FM, Rousseau JA, Lecomte R, Gascon S, Arany Z, Ky B, Force T, Knuuti J, Gallagher WM, Roivainen A, Byrne AT. O'Farrell AC, et al. Among authors: shiels l. PLoS One. 2017 Jan 27;12(1):e0169964. doi: 10.1371/journal.pone.0169964. eCollection 2017. PLoS One. 2017. PMID: 28129334 Free PMC article.