Secretory activity of the brain and peripheral organs: Spontaneous and stimulated release of noradrenaline in the ontogenesis of rats

Dokl Biochem Biophys. 2016 Mar;467(1):153-6. doi: 10.1134/S1607672916020204. Epub 2016 May 20.

Abstract

Spontaneous and K(+)-stimulated release of noradrenaline from the hypothalamus, adrenal gland, and organ of Zuckerkandl under their flowing incubation was investigated in the perinatal period of ontogenesis of rats. The results suggest that, during the investigated period of ontogenesis, adrenal glands are the main source of noradrenaline in the blood, whereas the contributions of the organ of Zuckerkandl and the brain are not as significant and change during this period.

MeSH terms

  • Adrenal Glands / drug effects
  • Adrenal Glands / growth & development
  • Adrenal Glands / metabolism*
  • Adrenergic Agents / administration & dosage
  • Animals
  • Blood Chemical Analysis
  • Cations, Monovalent / administration & dosage
  • Chromatography, High Pressure Liquid
  • Hypothalamus / drug effects
  • Hypothalamus / growth & development
  • Hypothalamus / metabolism*
  • Male
  • Norepinephrine / metabolism*
  • Para-Aortic Bodies / drug effects
  • Para-Aortic Bodies / metabolism*
  • Potassium / administration & dosage
  • Rats, Wistar

Substances

  • Adrenergic Agents
  • Cations, Monovalent
  • Potassium
  • Norepinephrine