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An NFATc1/SMAD3/cJUN Complex Restricted to SMAD4-Deficient Pancreatic Cancer Guides Rational Therapies.
Hasselluhn MC, Schlösser D, Versemann L, Schmidt GE, Ulisse M, Oschwald J, Zhang Z, Hamdan F, Xiao H, Kopp W, Spitalieri J, Kellner C, Schneider C, Reutlinger K, Nagarajan S, Steuber B, Sastra SA, Palermo CF, Appelhans J, Bohnenberger H, Todorovic J, Kostyuchek I, Ströbel P, Bockelmann A, König A, Ammer-Herrmenau C, Schmidleitner L, Kaulfuß S, Wollnik B, Hahn SA, Neesse A, Singh SK, Bastians H, Reichert M, Sax U, Olive KP, Johnsen SA, Schneider G, Ellenrieder V, Hessmann E. Hasselluhn MC, et al. Among authors: versemann l. Gastroenterology. 2024 Feb;166(2):298-312.e14. doi: 10.1053/j.gastro.2023.10.026. Epub 2023 Oct 31. Gastroenterology. 2024. PMID: 37913894
TP53-Status-Dependent Oncogenic EZH2 Activity in Pancreatic Cancer.
Versemann L, Patil S, Steuber B, Zhang Z, Kopp W, Krawczyk HE, Kaulfuß S, Wollnik B, Ströbel P, Neesse A, Singh SK, Ellenrieder V, Hessmann E. Versemann L, et al. Cancers (Basel). 2022 Jul 15;14(14):3451. doi: 10.3390/cancers14143451. Cancers (Basel). 2022. PMID: 35884510 Free PMC article.
Chromatin-Independent Interplay of NFATc1 and EZH2 in Pancreatic Cancer.
Patil S, Forster T, Reutlinger K, Kopp W, Versemann L, Spitalieri J, Gaedcke J, Ströbel P, Singh SK, Ellenrieder V, Neesse A, Hessmann E. Patil S, et al. Among authors: versemann l. Cells. 2021 Dec 8;10(12):3463. doi: 10.3390/cells10123463. Cells. 2021. PMID: 34943970 Free PMC article.
EZH2 Regulates Pancreatic Cancer Subtype Identity and Tumor Progression via Transcriptional Repression of GATA6.
Patil S, Steuber B, Kopp W, Kari V, Urbach L, Wang X, Küffer S, Bohnenberger H, Spyropoulou D, Zhang Z, Versemann L, Bösherz MS, Brunner M, Gaedcke J, Ströbel P, Zhang JS, Neesse A, Ellenrieder V, Singh SK, Johnsen SA, Hessmann E. Patil S, et al. Among authors: versemann l. Cancer Res. 2020 Nov 1;80(21):4620-4632. doi: 10.1158/0008-5472.CAN-20-0672. Epub 2020 Sep 9. Cancer Res. 2020. PMID: 32907838