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Page 1
The Orai Pore Opening Mechanism.
Tiffner A, Maltan L, Weiß S, Derler I. Tiffner A, et al. Among authors: maltan l. Int J Mol Sci. 2021 Jan 7;22(2):533. doi: 10.3390/ijms22020533. Int J Mol Sci. 2021. PMID: 33430308 Free PMC article. Review.
The Role of Lipids in CRAC Channel Function.
Maltan L, Andova AM, Derler I. Maltan L, et al. Biomolecules. 2022 Feb 23;12(3):352. doi: 10.3390/biom12030352. Biomolecules. 2022. PMID: 35327543 Free PMC article. Review.
Critical parameters maintaining authentic CRAC channel hallmarks.
Krizova A, Maltan L, Derler I. Krizova A, et al. Among authors: maltan l. Eur Biophys J. 2019 Jul;48(5):425-445. doi: 10.1007/s00249-019-01355-6. Epub 2019 Mar 21. Eur Biophys J. 2019. PMID: 30903264 Free PMC article. Review.
Orai1 Boosts SK3 Channel Activation.
Tiffner A, Hopl V, Schober R, Sallinger M, Grabmayr H, Höglinger C, Fahrner M, Lunz V, Maltan L, Frischauf I, Krivic D, Bhardwaj R, Schindl R, Hediger MA, Derler I. Tiffner A, et al. Among authors: maltan l. Cancers (Basel). 2021 Dec 17;13(24):6357. doi: 10.3390/cancers13246357. Cancers (Basel). 2021. PMID: 34944977 Free PMC article.
Swing-out opening of stromal interaction molecule 1.
Horvath F, Berlansky S, Maltan L, Grabmayr H, Fahrner M, Derler I, Romanin C, Renger T, Krobath H. Horvath F, et al. Among authors: maltan l. Protein Sci. 2023 Mar;32(3):e4571. doi: 10.1002/pro.4571. Protein Sci. 2023. PMID: 36691702 Free PMC article.
Photocrosslinking-induced CRAC channel-like Orai1 activation independent of STIM1.
Maltan L, Weiß S, Najjar H, Leopold M, Lindinger S, Höglinger C, Höbarth L, Sallinger M, Grabmayr H, Berlansky S, Krivic D, Hopl V, Blaimschein A, Fahrner M, Frischauf I, Tiffner A, Derler I. Maltan L, et al. Nat Commun. 2023 Mar 8;14(1):1286. doi: 10.1038/s41467-023-36458-4. Nat Commun. 2023. PMID: 36890174 Free PMC article.
CRAC channel opening is determined by a series of Orai1 gating checkpoints in the transmembrane and cytosolic regions.
Tiffner A, Schober R, Höglinger C, Bonhenry D, Pandey S, Lunz V, Sallinger M, Frischauf I, Fahrner M, Lindinger S, Maltan L, Berlansky S, Stadlbauer M, Schindl R, Ettrich R, Romanin C, Derler I. Tiffner A, et al. Among authors: maltan l. J Biol Chem. 2021 Jan-Jun;296:100224. doi: 10.1074/jbc.RA120.015548. Epub 2020 Dec 29. J Biol Chem. 2021. PMID: 33361160 Free PMC article.