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Page 1
Showing results for lean zhang
Search for Leian Zhang instead (2 results)
Predicted fat mass and lean mass in relation to all-cause and cause-specific mortality.
Liu M, Zhang Z, Zhou C, Ye Z, He P, Zhang Y, Li H, Liu C, Qin X. Liu M, et al. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1064-1075. doi: 10.1002/jcsm.12921. Epub 2022 Jan 23. J Cachexia Sarcopenia Muscle. 2022. PMID: 35068076 Free PMC article.
In contrast, predicted lean mass showed a L-shaped association with all-cause mortality, with higher mortality in those with lower lean mass: Quintile 1 (HR, 1.64; 95% CI: 1.46-1.83) and Quintile 2 (HR, 1.29; 95% CI: 1.18-1.42) compared with Quintile 3. ...CONCLUSIO …
In contrast, predicted lean mass showed a L-shaped association with all-cause mortality, with higher mortality in those with lower …
The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.
Pei YF, Liu YZ, Yang XL, Zhang H, Feng GJ, Wei XT, Zhang L. Pei YF, et al. Commun Biol. 2020 Oct 23;3(1):608. doi: 10.1038/s42003-020-01334-0. Commun Biol. 2020. PMID: 33097823 Free PMC article.
Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but its genetic determinants are largely unknown. ...Polygenic risk score prediction well distinguished participants with high and low ALM. The fi …
Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but it …
Lean nonalcoholic fatty liver disease and sarcopenia.
Chen M, Cao Y, Ji G, Zhang L. Chen M, et al. Front Endocrinol (Lausanne). 2023 Jun 23;14:1217249. doi: 10.3389/fendo.2023.1217249. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37424859 Free PMC article. Review.
The risk factor for NAFLD is often considered to be obesity, but it can also occur in people with lean type, which is defined as lean NAFLD. Lean NAFLD is commonly associated with sarcopenia, a progressive loss of muscle quantity and quality. ...Therefore, we …
The risk factor for NAFLD is often considered to be obesity, but it can also occur in people with lean type, which is defined as l …
Decreased Abundance of Akkermansia muciniphila Leads to the Impairment of Insulin Secretion and Glucose Homeostasis in Lean Type 2 Diabetes.
Zhang J, Ni Y, Qian L, Fang Q, Zheng T, Zhang M, Gao Q, Zhang Y, Ni J, Hou X, Bao Y, Kovatcheva-Datchary P, Xu A, Li H, Panagiotou G, Jia W. Zhang J, et al. Adv Sci (Weinh). 2021 Aug;8(16):e2100536. doi: 10.1002/advs.202100536. Epub 2021 Jun 4. Adv Sci (Weinh). 2021. PMID: 34085773 Free PMC article.
Several studies have linked the gut microbiome to obesity and T2D, but the role of gut microbiota in lean individuals with T2D having unique clinical characteristics remains unclear. A metagenomic and targeted metabolomic analysis is conducted in 182 lean and abdomi …
Several studies have linked the gut microbiome to obesity and T2D, but the role of gut microbiota in lean individuals with T2D having …
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. Kumar A, et al. Nat Commun. 2021 Jan 11;12(1):213. doi: 10.1038/s41467-020-20500-w. Nat Commun. 2021. PMID: 33431899 Free PMC article.
How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being administered exosomes isolated from the feces of obese mice fed a HFD or from patients with type II diabetes. HFD altered the lipid composition …
How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being adm …
Positional cloning of the mouse obese gene and its human homologue.
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Zhang Y, et al. Nature. 1994 Dec 1;372(6505):425-32. doi: 10.1038/372425a0. Nature. 1994. PMID: 7984236
The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules that regulates energy balance in the mouse is the obese (ob) gene. ...
The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules …
Alterations in the Gut Virome in Obesity and Type 2 Diabetes Mellitus.
Yang K, Niu J, Zuo T, Sun Y, Xu Z, Tang W, Liu Q, Zhang J, Ng EKW, Wong SKH, Yeoh YK, Chan PKS, Chan FKL, Miao Y, Ng SC. Yang K, et al. Gastroenterology. 2021 Oct;161(4):1257-1269.e13. doi: 10.1053/j.gastro.2021.06.056. Epub 2021 Jun 25. Gastroenterology. 2021. PMID: 34175280
Gut virome, bacteriome, and viral-bacterial correlations were compared between obese subjects and lean controls. RESULTS: Obese subjects, especially those with T2DM (ObT2), had a decreased gut viral richness and diversity compared with lean controls in the Hong Kong …
Gut virome, bacteriome, and viral-bacterial correlations were compared between obese subjects and lean controls. RESULTS: Obese subje …
Clinical characterization and proteomic profiling of lean nonalcoholic fatty liver disease.
Jiang Y, Zhuang X, Zhang J, Li M, Du S, Tian J, Yuan Y, Ji G, Hu C. Jiang Y, et al. Front Endocrinol (Lausanne). 2023 Nov 16;14:1171397. doi: 10.3389/fendo.2023.1171397. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 38034020 Free PMC article.
The lean NAFLD group was compared to both lean healthy and obese NAFLD groups across all data. RESULTS AND DISCUSSION: The results indicated that the lean NAFLD group exhibited intermediate metabolic profiles, falling between those of the lean healthy …
The lean NAFLD group was compared to both lean healthy and obese NAFLD groups across all data. RESULTS AND DISCUSSION: The res …
Long-term outcomes in lean and non-lean NAFLD patients: a systematic review and meta-analysis.
Huang S, Bao Y, Zhang N, Niu R, Tian L. Huang S, et al. Endocrine. 2023 May 30. doi: 10.1007/s12020-023-03351-5. Online ahead of print. Endocrine. 2023. PMID: 37253855
Our primary outcome was to compare the all-cause mortality in lean NAFLD patients and non-lean NAFLD patients by qualitative synthesis. ...RESULTS: We identified 12 studies (n = 26,329), 7 of which (n = 7924) were used to evaluate the risk of all-cause mortality bet …
Our primary outcome was to compare the all-cause mortality in lean NAFLD patients and non-lean NAFLD patients by qualitative s …
1,471 results