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Page 1
Showing results for lean zhang
Search for Leian Zhang instead (2 results)
Predicted fat mass and lean mass in relation to all-cause and cause-specific mortality.
Liu M, Zhang Z, Zhou C, Ye Z, He P, Zhang Y, Li H, Liu C, Qin X. Liu M, et al. J Cachexia Sarcopenia Muscle. 2022 Apr;13(2):1064-1075. doi: 10.1002/jcsm.12921. Epub 2022 Jan 23. J Cachexia Sarcopenia Muscle. 2022. PMID: 35068076 Free PMC article.
In contrast, predicted lean mass showed a L-shaped association with all-cause mortality, with higher mortality in those with lower lean mass: Quintile 1 (HR, 1.64; 95% CI: 1.46-1.83) and Quintile 2 (HR, 1.29; 95% CI: 1.18-1.42) compared with Quintile 3. ...CONCLUSIO …
In contrast, predicted lean mass showed a L-shaped association with all-cause mortality, with higher mortality in those with lower …
Lean nonalcoholic fatty liver disease and sarcopenia.
Chen M, Cao Y, Ji G, Zhang L. Chen M, et al. Front Endocrinol (Lausanne). 2023 Jun 23;14:1217249. doi: 10.3389/fendo.2023.1217249. eCollection 2023. Front Endocrinol (Lausanne). 2023. PMID: 37424859 Free PMC article. Review.
The risk factor for NAFLD is often considered to be obesity, but it can also occur in people with lean type, which is defined as lean NAFLD. Lean NAFLD is commonly associated with sarcopenia, a progressive loss of muscle quantity and quality. ...Therefore, we …
The risk factor for NAFLD is often considered to be obesity, but it can also occur in people with lean type, which is defined as l …
High-fat diet-induced upregulation of exosomal phosphatidylcholine contributes to insulin resistance.
Kumar A, Sundaram K, Mu J, Dryden GW, Sriwastva MK, Lei C, Zhang L, Qiu X, Xu F, Yan J, Zhang X, Park JW, Merchant ML, Bohler HCL, Wang B, Zhang S, Qin C, Xu Z, Han X, McClain CJ, Teng Y, Zhang HG. Kumar A, et al. Nat Commun. 2021 Jan 11;12(1):213. doi: 10.1038/s41467-020-20500-w. Nat Commun. 2021. PMID: 33431899 Free PMC article.
How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being administered exosomes isolated from the feces of obese mice fed a HFD or from patients with type II diabetes. HFD altered the lipid composition …
How high-fat diet causes insulin resistance is largely unknown. Here, we show that lean mice become insulin resistant after being adm …
The genetic architecture of appendicular lean mass characterized by association analysis in the UK Biobank study.
Pei YF, Liu YZ, Yang XL, Zhang H, Feng GJ, Wei XT, Zhang L. Pei YF, et al. Commun Biol. 2020 Oct 23;3(1):608. doi: 10.1038/s42003-020-01334-0. Commun Biol. 2020. PMID: 33097823 Free PMC article.
Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but its genetic determinants are largely unknown. ...Polygenic risk score prediction well distinguished participants with high and low ALM. The fi …
Appendicular lean mass (ALM) is a heritable trait associated with loss of lean muscle mass and strength, or sarcopenia, but it …
Lean adipose tissue macrophage derived exosome confers immunoregulation to improve wound healing in diabetes.
Xia W, Liu Y, Jiang X, Li M, Zheng S, Zhang Z, Huang X, Luo S, Khoong Y, Hou M, Zan T. Xia W, et al. J Nanobiotechnology. 2023 Apr 12;21(1):128. doi: 10.1186/s12951-023-01869-4. J Nanobiotechnology. 2023. PMID: 37046252 Free PMC article.
The miRs sequence of tissue samples from wounds treated with Exos secreted by lean ATMs (Exos(Lean)) revealed that miR-222-3p was up-regulated. Further analyses showed that inhibiting miR-222-3p using a miR inhibitor impaired the macrophage-reprogramming effect of E …
The miRs sequence of tissue samples from wounds treated with Exos secreted by lean ATMs (Exos(Lean)) revealed that miR-222-3p …
Positional cloning of the mouse obese gene and its human homologue.
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. Zhang Y, et al. Nature. 1994 Dec 1;372(6505):425-32. doi: 10.1038/372425a0. Nature. 1994. PMID: 7984236
The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules that regulates energy balance in the mouse is the obese (ob) gene. ...
The mechanisms that balance food intake and energy expenditure determine who will be obese and who will be lean. One of the molecules …
Low lean mass with obesity in older adults with hypertension: prevalence and association with mortality rate.
Qu Q, Guo Q, Sun J, Lu X, Cheang I, Zhu X, Yao W, Li X, Zhang H, Zhou Y, Liao S, Gao R. Qu Q, et al. BMC Geriatr. 2023 Oct 3;23(1):619. doi: 10.1186/s12877-023-04326-x. BMC Geriatr. 2023. PMID: 37789259 Free PMC article.
METHODS: We included 1105 hypertensive patients aged 60 years from the National Health and Nutrition Examination Survey 1999-2004. Sarcopenia was broadly defined based on low lean mass (LLM; as measured by dual-energy X-ray absorptiometry), and was defined using appendicul …
METHODS: We included 1105 hypertensive patients aged 60 years from the National Health and Nutrition Examination Survey 1999-2004. Sarcopeni …
Genetic variants in HFE are associated with non-alcoholic fatty liver disease in lean individuals.
Sun Z, Pan X, Tian A, Surakka I, Wang T, Jiao X, He S, Song J, Tian X, Tong D, Wen J, Zhang Y, Liu W, Chen P. Sun Z, et al. JHEP Rep. 2023 Mar 27;5(7):100744. doi: 10.1016/j.jhepr.2023.100744. eCollection 2023 Jul. JHEP Rep. 2023. PMID: 37235137 Free PMC article.
BACKGROUND & AIMS: Around 20% of patients with non-alcoholic fatty liver disease (NAFLD) are lean. Increasing evidence suggests that lean NAFLD is a unique subtype of the disease. ...Type 2 diabetes was the most pronounced clinical sequela of lean NAFLD, …
BACKGROUND & AIMS: Around 20% of patients with non-alcoholic fatty liver disease (NAFLD) are lean. Increasing evidence suggests t …
Alterations in the Gut Virome in Obesity and Type 2 Diabetes Mellitus.
Yang K, Niu J, Zuo T, Sun Y, Xu Z, Tang W, Liu Q, Zhang J, Ng EKW, Wong SKH, Yeoh YK, Chan PKS, Chan FKL, Miao Y, Ng SC. Yang K, et al. Gastroenterology. 2021 Oct;161(4):1257-1269.e13. doi: 10.1053/j.gastro.2021.06.056. Epub 2021 Jun 25. Gastroenterology. 2021. PMID: 34175280
Gut virome, bacteriome, and viral-bacterial correlations were compared between obese subjects and lean controls. RESULTS: Obese subjects, especially those with T2DM (ObT2), had a decreased gut viral richness and diversity compared with lean controls in the Hong Kong …
Gut virome, bacteriome, and viral-bacterial correlations were compared between obese subjects and lean controls. RESULTS: Obese subje …
1,441 results