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Human Thymidylate Synthase Inhibitors Halting Ovarian Cancer Growth.
Ferrari S, Severi L, Pozzi C, Quotadamo A, Ponterini G, Losi L, Marverti G, Costi MP. Ferrari S, et al. Among authors: severi l. Vitam Horm. 2018;107:473-513. doi: 10.1016/bs.vh.2017.12.002. Epub 2018 Feb 12. Vitam Horm. 2018. PMID: 29544641 Review.
Serum Mass Spectrometry Proteomics and Protein Set Identification in Response to FOLFOX-4 in Drug-Resistant Ovarian Carcinoma.
D'Arca D, Severi L, Ferrari S, Dozza L, Marverti G, Magni F, Chinello C, Pagani L, Tagliazucchi L, Villani M, d'Addese G, Piga I, Conteduca V, Rossi L, Gurioli G, De Giorgi U, Losi L, Costi MP. D'Arca D, et al. Among authors: severi l. Cancers (Basel). 2023 Jan 8;15(2):412. doi: 10.3390/cancers15020412. Cancers (Basel). 2023. PMID: 36672361 Free PMC article.
Conformational Propensity and Biological Studies of Proline Mutated LR Peptides Inhibiting Human Thymidylate Synthase and Ovarian Cancer Cell Growth.
Saxena P, Severi L, Santucci M, Taddia L, Ferrari S, Luciani R, Marverti G, Marraccini C, Tondi D, Mor M, Scalvini L, Vitiello S, Losi L, Fonda S, Pacifico S, Guerrini R, D'Arca D, Ponterini G, Costi MP. Saxena P, et al. Among authors: severi l. J Med Chem. 2018 Aug 23;61(16):7374-7380. doi: 10.1021/acs.jmedchem.7b01699. Epub 2018 Aug 13. J Med Chem. 2018. PMID: 30035541
A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells.
Marverti G, Gozzi G, Maretti E, Lauriola A, Severi L, Sacchetti F, Losi L, Pacifico S, Ferrari S, Ponterini G, Leo E, Costi MP, D'Arca D. Marverti G, et al. Among authors: severi l. Int J Mol Sci. 2020 Jun 23;21(12):4452. doi: 10.3390/ijms21124452. Int J Mol Sci. 2020. PMID: 32585842 Free PMC article.
Discovery of a benzothiophene-flavonol halting miltefosine and antimonial drug resistance in Leishmania parasites through the application of medicinal chemistry, screening and genomics.
Borsari C, Jiménez-Antón MD, Eick J, Bifeld E, Torrado JJ, Olías-Molero AI, Corral MJ, Santarem N, Baptista C, Severi L, Gul S, Wolf M, Kuzikov M, Ellinger B, Reinshagen J, Witt G, Linciano P, Tait A, Costantino L, Luciani R, Tejera Nevado P, Zander-Dinse D, Franco CH, Ferrari S, Moraes CB, Cordeiro-da-Silva A, Ponterini G, Clos J, Alunda JM, Costi MP. Borsari C, et al. Among authors: severi l. Eur J Med Chem. 2019 Dec 1;183:111676. doi: 10.1016/j.ejmech.2019.111676. Epub 2019 Sep 5. Eur J Med Chem. 2019. PMID: 31542713
Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer.
Severi L, Losi L, Fonda S, Taddia L, Gozzi G, Marverti G, Magni F, Chinello C, Stella M, Sheouli J, Braicu EI, Genovese F, Lauriola A, Marraccini C, Gualandi A, D'Arca D, Ferrari S, Costi MP. Severi L, et al. Front Pharmacol. 2018 May 8;9:454. doi: 10.3389/fphar.2018.00454. eCollection 2018. Front Pharmacol. 2018. PMID: 29867465 Free PMC article.