COVID-19 in Lung Transplant Recipients: A Report on 10 Recent Cases

Viruses. 2024 Apr 29;16(5):709. doi: 10.3390/v16050709.

Abstract

Due to immunosuppression, transplant recipients are at higher risk of infections with SARS-CoV-2 and worse clinical outcomes than immunocompetent hosts. Furthermore, lung transplant patients represent a special group among solid organ recipients, since pneumonia is the main manifestation of COVID-19. However, data on the course of disease and the changes in morbidity and mortality during the course of the pandemic are limited. In our pulmonary rehabilitation clinic, we treat patients shortly after lung transplant as well as long-term transplant patients. Over the last almost 4 years of pandemic, we witnessed several COVID-19 infections in lung transplant patients in our clinic as well as patients who acquired an infection beforehand. In this paper, we aim at retrospectively describing a series of recent COVID-19 cases in our clinic, looking at the clinical course of disease and outcomes in lung transplant patients.

Keywords: COVID-19; Remdesivir; immunosuppression; lung transplant.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • COVID-19* / epidemiology
  • Female
  • Humans
  • Immunocompromised Host
  • Lung Transplantation* / adverse effects
  • Male
  • Middle Aged
  • Retrospective Studies
  • SARS-CoV-2*
  • Transplant Recipients*

Grants and funding

This research received no external funding.