Layla A. Al-Kharashi - Search Results

Year	Number of Results
2017	1
2018	1
2019	1
2021	1
2022	2
2023	4
2024	1

1

Eugenol modulates genomic methylation and inactivates breast cancer-associated fibroblasts through E2F1-dependent downregulation of DNMT1/DNMT3A.

Al-Kharashi LA, Bakheet T, AlHarbi WA, Al-Moghrabi N, Aboussekhra A. Al-Kharashi LA, et al. Mol Carcinog. 2021 Nov;60(11):784-795. doi: 10.1002/mc.23344. Epub 2021 Sep 2. Mol Carcinog. 2021. PMID: 34473867

2

High DNMT1 Expression in Stromal Fibroblasts Promotes Angiogenesis and Unfavorable Outcome in Locally Advanced Breast Cancer Patients.

Al-Kharashi LA, Tulbah A, Arafah M, Eldali AM, Al-Tweigeri T, Aboussekhra A. Al-Kharashi LA, et al. Front Oncol. 2022 Jun 2;12:877219. doi: 10.3389/fonc.2022.877219. eCollection 2022. Front Oncol. 2022. PMID: 35719957 Free PMC article.

3

Formulation of Chitosan-Coated Brigatinib Nanospanlastics: Optimization, Characterization, Stability Assessment and In-Vitro Cytotoxicity Activity against H-1975 Cell Lines.

Zaki RM, Alfadhel MM, Alshahrani SM, Alsaqr A, Al-Kharashi LA, Anwer MK. Zaki RM, et al. Among authors: al kharashi la. Pharmaceuticals (Basel). 2022 Mar 13;15(3):348. doi: 10.3390/ph15030348. Pharmaceuticals (Basel). 2022. PMID: 35337145 Free PMC article.

4

TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity.

Badr AM, Al-Kharashi LA, Attia H, Alshehri S, Alajami HN, Ali RA, Mahran YF. Badr AM, et al. Among authors: al kharashi la. Pharmaceuticals (Basel). 2023 Feb 22;16(3):337. doi: 10.3390/ph16030337. Pharmaceuticals (Basel). 2023. PMID: 36986437 Free PMC article.

5

The DNA methyl-transferase protein DNMT1 enhances tumor-promoting properties of breast stromal fibroblasts.

Al-Kharashi LA, Al-Mohanna FH, Tulbah A, Aboussekhra A. Al-Kharashi LA, et al. Oncotarget. 2017 Dec 18;9(2):2329-2343. doi: 10.18632/oncotarget.23411. eCollection 2018 Jan 5. Oncotarget. 2017. PMID: 29416775 Free PMC article.

6

BALB/c and C57BL/6 mice differ in oxidant and antioxidant responses in innate and adaptive immune cells in an asthma model induced by cockroach allergens.

Al-Kharashi LA, Alqarni SA, Ahmad SF, Al-Harbi NO, Alsanea S, Ibrahim KE, Algahtani MM, Alhazzani K, Shazly GA, Al-Harbi MM, Nadeem A. Al-Kharashi LA, et al. Int Immunopharmacol. 2023 Nov;124(Pt B):110892. doi: 10.1016/j.intimp.2023.110892. Epub 2023 Sep 15. Int Immunopharmacol. 2023. PMID: 37717317

7

Decorin (DCN) Downregulation Activates Breast Stromal Fibroblasts and Promotes Their Pro-Carcinogenic Effects through the IL-6/STAT3/AUF1 Signaling.

Aljagthmi WA, Alasmari MA, Daghestani MH, Al-Kharashi LA, Al-Mohanna FH, Aboussekhra A. Aljagthmi WA, et al. Among authors: al kharashi la. Cells. 2024 Apr 14;13(8):680. doi: 10.3390/cells13080680. Cells. 2024. PMID: 38667295 Free PMC article.

8

Auranofin Modulates Thioredoxin Reductase/Nrf2 Signaling in Peripheral Immune Cells and the CNS in a Mouse Model of Relapsing-Remitting EAE.

Al-Kharashi LA, Al-Harbi NO, Ahmad SF, Attia SM, Algahtani MM, Ibrahim KE, Bakheet SA, Alanazi MM, Alqarni SA, Alsanea S, Nadeem A. Al-Kharashi LA, et al. Biomedicines. 2023 Sep 10;11(9):2502. doi: 10.3390/biomedicines11092502. Biomedicines. 2023. PMID: 37760943 Free PMC article.

9

The potent immunomodulatory compound VGX-1027 regulates inflammatory mediators in CD4⁺ T cells, which are concomitant with the prevention of neuroimmune dysregulation in BTBR T⁺ Itpr3^tf/J mice.

Ahmad SF, Nadeem A, Ansari MA, Bakheet SA, Alasmari F, Alasmari AF, Al-Kharashi LA, Al-Qahtani QH, Attia SM. Ahmad SF, et al. Among authors: al kharashi la. Life Sci. 2019 Nov 15;237:116930. doi: 10.1016/j.lfs.2019.116930. Epub 2019 Oct 11. Life Sci. 2019. PMID: 31610190

10

Radioprotective Effects of Carvacrol and/or Thymol against Gamma Irradiation-Induced Acute Nephropathy: In Silico and In Vivo Evidence of the Involvement of Insulin-like Growth Factor-1 (IGF-1) and Calcitonin Gene-Related Peptide.

Mahran YF, Al-Kharashi LA, Atawia RT, Alanazi RT, Dhahi AMB, Alsubaie R, Badr AM. Mahran YF, et al. Among authors: al kharashi la. Biomedicines. 2023 Sep 13;11(9):2521. doi: 10.3390/biomedicines11092521. Biomedicines. 2023. PMID: 37760962 Free PMC article.

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