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Page 1
Autoantibody subclass predominance is not driven by aberrant class switching or impaired B cell development.
Paardekooper LM, Fillié-Grijpma YE, van der Sluijs-Gelling AJ, Zlei M, van Doorn R, Vermeer MH, Paunovic M, Titulaer MJ, van der Maarel SM, van Dongen JJM, Verschuuren JJ, Huijbers MG; T2B consortium. Paardekooper LM, et al. Clin Immunol. 2023 Dec;257:109817. doi: 10.1016/j.clim.2023.109817. Epub 2023 Nov 2. Clin Immunol. 2023. PMID: 37925120 Free article.
Lipid peroxidation causes endosomal antigen release for cross-presentation.
Dingjan I, Verboogen DR, Paardekooper LM, Revelo NH, Sittig SP, Visser LJ, Mollard GF, Henriet SS, Figdor CG, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: paardekooper lm. Sci Rep. 2016 Feb 24;6:22064. doi: 10.1038/srep22064. Sci Rep. 2016. PMID: 26907999 Free PMC article.
Ethylene, an early marker of systemic inflammation in humans.
Paardekooper LM, van den Bogaart G, Kox M, Dingjan I, Neerincx AH, Bendix MB, Beest MT, Harren FJM, Risby T, Pickkers P, Marczin N, Cristescu SM. Paardekooper LM, et al. Sci Rep. 2017 Jul 31;7(1):6889. doi: 10.1038/s41598-017-05930-9. Sci Rep. 2017. PMID: 28761087 Free PMC article.
Hypoxia and TLR9 activation drive CXCL4 production in systemic sclerosis plasmacytoid dendritic cells via mtROS and HIF-2α.
Ottria A, Zimmermann M, Paardekooper LM, Carvalheiro T, Vazirpanah N, Silva-Cardoso S, Affandi AJ, Chouri E, V D Kroef M, Tieland RG, Bekker CPJ, Wichers CGK, Rossato M, Mocholi-Gimeno E, Tekstra J, Ton E, van Laar JM, Cossu M, Beretta L, Garcia Perez S, Pandit A, Bonte-Mineur F, Reedquist KA, van den Bogaart G, Radstake TRDJ, Marut W. Ottria A, et al. Among authors: paardekooper lm. Rheumatology (Oxford). 2022 May 30;61(6):2682-2693. doi: 10.1093/rheumatology/keab532. Rheumatology (Oxford). 2022. PMID: 34559222
VAMP8-mediated NOX2 recruitment to endosomes is necessary for antigen release.
Dingjan I, Paardekooper LM, Verboogen DRJ, von Mollard GF, Ter Beest M, van den Bogaart G. Dingjan I, et al. Among authors: paardekooper lm. Eur J Cell Biol. 2017 Oct;96(7):705-714. doi: 10.1016/j.ejcb.2017.06.007. Epub 2017 Jun 23. Eur J Cell Biol. 2017. PMID: 28688576 Free PMC article.