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Interactions between BRD4S, LOXL2, and MED1 drive cell cycle transcription in triple-negative breast cancer.
Pascual-Reguant L, Serra-Camprubí Q, Datta D, Cianferoni D, Kourtis S, Gañez-Zapater A, Cannatá C, Espinar L, Querol J, García-López L, Musa-Afaneh S, Guirola M, Gkanogiannis A, Miró Canturri A, Guzman M, Rodríguez O, Herencia-Ropero A, Arribas J, Serra V, Serrano L, Tian TV, Peiró S, Sdelci S. Pascual-Reguant L, et al. EMBO Mol Med. 2023 Dec 7;15(12):e18459. doi: 10.15252/emmm.202318459. Epub 2023 Nov 8. EMBO Mol Med. 2023. PMID: 37937685 Free PMC article.
A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability.
Moretton A, Kourtis S, Gañez Zapater A, Calabrò C, Espinar Calvo ML, Fontaine F, Darai E, Abad Cortel E, Block S, Pascual-Reguant L, Pardo-Lorente N, Ghose R, Vander Heiden MG, Janic A, Müller AC, Loizou JI, Sdelci S. Moretton A, et al. Among authors: pascual reguant l. Mol Syst Biol. 2023 Jul 11;19(7):e11267. doi: 10.15252/msb.202211267. Epub 2023 Jun 1. Mol Syst Biol. 2023. PMID: 37259925 Free PMC article.
From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation.
Ghose R, Aranguren-Ibáñez Á, Arecco N, Balboa D, Bataller M, Beltran S, Benisty H, Bénard A, Bernardo E, Carbonell Sala S, Casals E, Ciampi L, Condemi L, Corvó A, Cosín-Tomás M, Cuenca-Ardura M, Duran Serrano JM, Espejo Díaz MI, Fernandez Callejo M, Gañez-Zapater A, Garcia-Castellanos R, Garrido R, Henkin G, Hermoso Pulido T, Hernandez-Alias X, Herrero Vicente J, Ingham M, Lim WM, Llonch S, Marmesat Bertoli E, Miguel-Escalada I, Montero-Blay A, Navarrete Hernández C, Neguembor MV, Ní Chárthaigh RA, Pardo-Lorente N, Pascual-Reguant L, Pérez-Lluch S, Perza R, Pesaresi M, Picó Amador D, Pifarré P, Piscia D, Plana-Carmona M, Ponomarenko J, Radusky L, Rivero E, Rogalska M, Torcal Garcia G, Wojnacki J. Ghose R, et al. Among authors: pascual reguant l. F1000Res. 2020 Nov 16;9:1336. doi: 10.12688/f1000research.27497.1. eCollection 2020. F1000Res. 2020. PMID: 34745570 Free PMC article.
LOXL2-mediated chromatin compaction is required to maintain the oncogenic properties of triple-negative breast cancer cells.
Serra-Bardenys G, Blanco E, Escudero-Iriarte C, Serra-Camprubí Q, Querol J, Pascual-Reguant L, Morancho B, Escorihuela M, Tissera NS, Sabé A, Martín L, Segura-Bayona S, Verde G, Aiese Cigliano R, Millanes-Romero A, Jerónimo C, Cebrià-Costa JP, Nuciforo P, Simonetti S, Viaplana C, Dienstmann R, Oliveira M, Peg V, Stracker TH, Arribas J, Canals F, Villanueva J, Di Croce L, García de Herreros A, Tian TV, Peiró S. Serra-Bardenys G, et al. Among authors: pascual reguant l. FEBS J. 2024 Mar 7. doi: 10.1111/febs.17112. Online ahead of print. FEBS J. 2024. PMID: 38451841
Lysyl oxidase-like 2 (LOXL2) oxidizes trimethylated lysine 4 in histone H3.
Herranz N, Dave N, Millanes-Romero A, Pascual-Reguant L, Morey L, Díaz VM, Lórenz-Fonfría V, Gutierrez-Gallego R, Jerónimo C, Iturbide A, Di Croce L, García de Herreros A, Peiró S. Herranz N, et al. Among authors: pascual reguant l. FEBS J. 2016 Dec;283(23):4263-4273. doi: 10.1111/febs.13922. Epub 2016 Oct 30. FEBS J. 2016. PMID: 27735137 Free article.
Histone H1 depletion triggers an interferon response in cancer cells via activation of heterochromatic repeats.
Izquierdo-Bouldstridge A, Bustillos A, Bonet-Costa C, Aribau-Miralbés P, García-Gomis D, Dabad M, Esteve-Codina A, Pascual-Reguant L, Peiró S, Esteller M, Murtha M, Millán-Ariño L, Jordan A. Izquierdo-Bouldstridge A, et al. Among authors: pascual reguant l. Nucleic Acids Res. 2017 Nov 16;45(20):11622-11642. doi: 10.1093/nar/gkx746. Nucleic Acids Res. 2017. PMID: 28977426 Free PMC article.