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2004 1
2005 1
2008 1
2009 2
2010 2
2011 1
2012 2
2014 5
2015 4
2016 9
2017 4
2018 10
2019 6
2020 10
2021 6
2022 5
2023 4
2024 5

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72 results

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Page 1
Showing results for laura cascades
Search for Laura Casades instead (1 results)
Individualised neoantigen therapy mRNA-4157 (V940) plus pembrolizumab versus pembrolizumab monotherapy in resected melanoma (KEYNOTE-942): a randomised, phase 2b study.
Weber JS, Carlino MS, Khattak A, Meniawy T, Ansstas G, Taylor MH, Kim KB, McKean M, Long GV, Sullivan RJ, Faries M, Tran TT, Cowey CL, Pecora A, Shaheen M, Segar J, Medina T, Atkinson V, Gibney GT, Luke JJ, Thomas S, Buchbinder EI, Healy JA, Huang M, Morrissey M, Feldman I, Sehgal V, Robert-Tissot C, Hou P, Zhu L, Brown M, Aanur P, Meehan RS, Zaks T. Weber JS, et al. Lancet. 2024 Feb 17;403(10427):632-644. doi: 10.1016/S0140-6736(23)02268-7. Epub 2024 Jan 18. Lancet. 2024. PMID: 38246194 Clinical Trial.
TRAILblazing Strategies for Cancer Treatment.
Kretz AL, Trauzold A, Hillenbrand A, Knippschild U, Henne-Bruns D, von Karstedt S, Lemke J. Kretz AL, et al. Cancers (Basel). 2019 Mar 30;11(4):456. doi: 10.3390/cancers11040456. Cancers (Basel). 2019. PMID: 30935038 Free PMC article. Review.
TRAIL binds to its membrane-bound death receptors TRAIL-R1 (DR4) and TRAIL-R2 (DR5) inducing the formation of a death-inducing signalling complex (DISC) thereby activating the apoptotic cascade. The ability of TRAIL to also induce apoptosis independently of p53 makes TRAIL …
TRAIL binds to its membrane-bound death receptors TRAIL-R1 (DR4) and TRAIL-R2 (DR5) inducing the formation of a death-inducing signalling co …
ApoCIII: A multifaceted protein in cardiometabolic disease.
D'Erasmo L, Di Costanzo A, Gallo A, Bruckert E, Arca M. D'Erasmo L, et al. Metabolism. 2020 Dec;113:154395. doi: 10.1016/j.metabol.2020.154395. Epub 2020 Oct 12. Metabolism. 2020. PMID: 33058850 Review.
Indeed, ApoCIII has been implicated in other physiological processes such as glucose homeostasis, monocyte adhesion, activation of inflammatory pathways, and modulation of the coagulation cascade. As the inhibition of ApoCIII is emerging as a new promising therapeutic stra …
Indeed, ApoCIII has been implicated in other physiological processes such as glucose homeostasis, monocyte adhesion, activation of inflammat …
Taste Receptors: New Players in Sperm Biology.
Luddi A, Governini L, Wilmskötter D, Gudermann T, Boekhoff I, Piomboni P. Luddi A, et al. Int J Mol Sci. 2019 Feb 22;20(4):967. doi: 10.3390/ijms20040967. Int J Mol Sci. 2019. PMID: 30813355 Free PMC article. Review.
The recent observation that taste receptors and components of the coupled taste transduction cascade are also expressed during the different phases of spermatogenesis as well as in mature spermatozoa from mouse to humans and the overlap between the ligand spectrum of taste …
The recent observation that taste receptors and components of the coupled taste transduction cascade are also expressed during the di …
Immune asynchrony in COVID-19 pathogenesis and potential immunotherapies.
Zhou T, Su TT, Mudianto T, Wang J. Zhou T, et al. J Exp Med. 2020 Oct 5;217(10):e20200674. doi: 10.1084/jem.20200674. J Exp Med. 2020. PMID: 32910820 Free PMC article. Review.
Spatiotemporal control of the quality and quantity of the antiviral immune responses involves synchronized cellular and molecular cascades and cross-talk between innate and adaptive immunity. Dysregulated responses in immunity, such as at the stages of immune sensing, alar …
Spatiotemporal control of the quality and quantity of the antiviral immune responses involves synchronized cellular and molecular cascade
The role of stress in the mosaic of autoimmunity: An overlooked association.
Sharif K, Watad A, Coplan L, Lichtbroun B, Krosser A, Lichtbroun M, Bragazzi NL, Amital H, Afek A, Shoenfeld Y. Sharif K, et al. Autoimmun Rev. 2018 Oct;17(10):967-983. doi: 10.1016/j.autrev.2018.04.005. Epub 2018 Aug 14. Autoimmun Rev. 2018. PMID: 30118900 Review.
Genetic factors as well as environmental factors appear to interplay, leading to a cascade of events resulting in disease onset. Stress has been postulated to play a role in disease onset in the genetically susceptible patients. ...
Genetic factors as well as environmental factors appear to interplay, leading to a cascade of events resulting in disease onset. Stre …
Infection and preterm birth.
Klein LL, Gibbs RS. Klein LL, et al. Obstet Gynecol Clin North Am. 2005 Sep;32(3):397-410. doi: 10.1016/j.ogc.2005.03.001. Obstet Gynecol Clin North Am. 2005. PMID: 16125040 Review.
Intrauterine infection leads to a maternal and fetal inflammatory cascade, which produces uterine contractions and may also result in long-term adverse outcomes, such as cerebral palsy. ...
Intrauterine infection leads to a maternal and fetal inflammatory cascade, which produces uterine contractions and may also result in …
β-arrestin1 at the cross-road of endothelin-1 signaling in cancer.
Rosanò L, Bagnato A. Rosanò L, et al. J Exp Clin Cancer Res. 2016 Jul 29;35(1):121. doi: 10.1186/s13046-016-0401-4. J Exp Clin Cancer Res. 2016. PMID: 27473335 Free PMC article. Review.
ET-1R are aberrantly expressed in human malignancies, potentially representing prognostic factors. Their activation by ligand stimulation initiate signaling cascades activating different downstream effectors, allowing precise control over multiple signaling pathways. ...
ET-1R are aberrantly expressed in human malignancies, potentially representing prognostic factors. Their activation by ligand stimulation in …
DNA-Based Enzyme Reactors and Systems.
Linko V, Nummelin S, Aarnos L, Tapio K, Toppari JJ, Kostiainen MA. Linko V, et al. Nanomaterials (Basel). 2016 Jul 27;6(8):139. doi: 10.3390/nano6080139. Nanomaterials (Basel). 2016. PMID: 28335267 Free PMC article. Review.
Currently, DNA-enzyme hybrids can be used to control (multi-enzyme) cascade reactions and to regulate the enzyme functions and the reaction pathways. ...
Currently, DNA-enzyme hybrids can be used to control (multi-enzyme) cascade reactions and to regulate the enzyme functions and the re …
Genetic Counseling and Family Screening Recommendations in Patients with Telomere Biology Disorders.
Ongie L, Raj HA, Stevens KB. Ongie L, et al. Curr Hematol Malig Rep. 2023 Dec;18(6):273-283. doi: 10.1007/s11899-023-00713-8. Epub 2023 Oct 3. Curr Hematol Malig Rep. 2023. PMID: 37787873 Review.
Here, we review the current literature surrounding genetic testing strategies, cascade testing, reproductive implications, and the role of genetic counseling. ...
Here, we review the current literature surrounding genetic testing strategies, cascade testing, reproductive implications, and the ro …
72 results