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The mechanism of action of a novel neuroprotective low molecular weight dextran sulphate: New platform therapy for neurodegenerative diseases like Amyotrophic Lateral Sclerosis.
Logan A, Belli A, Di Pietro V, Tavazzi B, Lazzarino G, Mangione R, Lazzarino G, Morano I, Qureshi O, Bruce L, Barnes NM, Nagy Z. Logan A, et al. Among authors: bruce l. Front Pharmacol. 2022 Aug 30;13:983853. doi: 10.3389/fphar.2022.983853. eCollection 2022. Front Pharmacol. 2022. PMID: 36110516 Free PMC article.
ILB®, a Low Molecular Weight Dextran Sulphate, Restores Glutamate Homeostasis, Amino Acid Metabolism and Neurocognitive Functions in a Rat Model of Severe Traumatic Brain Injury.
Lazzarino G, Di Pietro V, Rinaudo M, Nagy Z, Barnes NM, Bruce L, Signoretti S, Mangione R, Saab MW, Tavazzi B, Belli A, Lazzarino G, Amorini AM, Logan A. Lazzarino G, et al. Among authors: bruce l. Int J Mol Sci. 2022 Jul 30;23(15):8460. doi: 10.3390/ijms23158460. Int J Mol Sci. 2022. PMID: 35955592 Free PMC article.
ILB® Attenuates Clinical Symptoms and Serum Biomarkers of Oxidative/Nitrosative Stress and Mitochondrial Dysfunction in Patients with Amyotrophic Lateral Sclerosis.
Lazzarino G, Mangione R, Belli A, Di Pietro V, Nagy Z, Barnes NM, Bruce L, Ropero BM, Persson LI, Manca B, Saab MW, Amorini AM, Tavazzi B, Lazzarino G, Logan A. Lazzarino G, et al. Among authors: bruce l. J Pers Med. 2021 Aug 14;11(8):794. doi: 10.3390/jpm11080794. J Pers Med. 2021. PMID: 34442438 Free PMC article.