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Page 1
Wnt Activation and Reduced Cell-Cell Contact Synergistically Induce Massive Expansion of Functional Human iPSC-Derived Cardiomyocytes.
Buikema JW, Lee S, Goodyer WR, Maas RG, Chirikian O, Li G, Miao Y, Paige SL, Lee D, Wu H, Paik DT, Rhee S, Tian L, Galdos FX, Puluca N, Beyersdorf B, Hu J, Beck A, Venkamatran S, Swami S, Wijnker P, Schuldt M, Dorsch LM, van Mil A, Red-Horse K, Wu JY, Geisen C, Hesse M, Serpooshan V, Jovinge S, Fleischmann BK, Doevendans PA, van der Velden J, Garcia KC, Wu JC, Sluijter JPG, Wu SM. Buikema JW, et al. Among authors: dorsch lm. Cell Stem Cell. 2020 Jul 2;27(1):50-63.e5. doi: 10.1016/j.stem.2020.06.001. Cell Stem Cell. 2020. PMID: 32619518 Free PMC article.
Untying the knot: protein quality control in inherited cardiomyopathies.
Dorsch LM, Schuldt M, Knežević D, Wiersma M, Kuster DWD, van der Velden J, Brundel BJJM. Dorsch LM, et al. Pflugers Arch. 2019 May;471(5):795-806. doi: 10.1007/s00424-018-2194-0. Epub 2018 Aug 14. Pflugers Arch. 2019. PMID: 30109411 Free PMC article. Review.
The microtubule signature in cardiac disease: etiology, disease stage, and age dependency.
Algül S, Dorsch LM, Sorop O, Vink A, Michels M, Dos Remedios CG, Dalinghaus M, Merkus D, Duncker DJ, Kuster DWD, van der Velden J. Algül S, et al. Among authors: dorsch lm. J Comp Physiol B. 2023 Oct;193(5):581-595. doi: 10.1007/s00360-023-01509-1. Epub 2023 Aug 29. J Comp Physiol B. 2023. PMID: 37644284 Free PMC article.
Characterization of heterozygous and homozygous mouse models with the most common hypertrophic cardiomyopathy mutation MYBPC3c.2373InsG in the Netherlands.
Hilderink S, Schuldt M, Goebel M, Jansen VJ, Manders E, Moorman S, Dorsch LM, van Steenbeek FG, van der Velden J, Kuster DWD. Hilderink S, et al. Among authors: dorsch lm. J Mol Cell Cardiol. 2023 Dec;185:65-76. doi: 10.1016/j.yjmcc.2023.10.008. Epub 2023 Oct 14. J Mol Cell Cardiol. 2023. PMID: 37844837 Free article.
Proteomic and Functional Studies Reveal Detyrosinated Tubulin as Treatment Target in Sarcomere Mutation-Induced Hypertrophic Cardiomyopathy.
Schuldt M, Pei J, Harakalova M, Dorsch LM, Schlossarek S, Mokry M, Knol JC, Pham TV, Schelfhorst T, Piersma SR, Dos Remedios C, Dalinghaus M, Michels M, Asselbergs FW, Moutin MJ, Carrier L, Jimenez CR, van der Velden J, Kuster DWD. Schuldt M, et al. Among authors: dorsch lm. Circ Heart Fail. 2021 Jan;14(1):e007022. doi: 10.1161/CIRCHEARTFAILURE.120.007022. Epub 2021 Jan 12. Circ Heart Fail. 2021. PMID: 33430602 Free PMC article.
The effect of tropomyosin variants on cardiomyocyte function and structure that underlie different clinical cardiomyopathy phenotypes.
Dorsch LM, Kuster DWD, Jongbloed JDH, Boven LG, van Spaendonck-Zwarts KY, Suurmeijer AJH, Vink A, du Marchie Sarvaas GJ, van den Berg MP, van der Velden J, Brundel BJJM, van der Zwaag PA. Dorsch LM, et al. Int J Cardiol. 2021 Jan 15;323:251-258. doi: 10.1016/j.ijcard.2020.08.101. Epub 2020 Sep 1. Int J Cardiol. 2021. PMID: 32882290 Free article.