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Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC).
EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC). Lancet. 2021 Nov 6;398(10312):1713-1725. doi: 10.1016/S0140-6736(21)01122-3. Epub 2021 Sep 7. Lancet. 2021. PMID: 34506743
Among patients receiving lipid-lowering medications, 16 803 (81.1%) were receiving statins and 3691 (21.2%) were on combination therapy, with greater use of more potent lipid-lowering medication in men than in women. Median LDL cholesterol was 5.43 mmol/L (IQR 4.32-6.72) a …
Among patients receiving lipid-lowering medications, 16 803 (81.1%) were receiving statins and 3691 (21.2%) were on combination therapy, wit …
Familial hypercholesterolaemia in children and adolescents from 48 countries: a cross-sectional study.
European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration. European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration. Lancet. 2024 Jan 6;403(10421):55-66. doi: 10.1016/S0140-6736(23)01842-1. Epub 2023 Dec 12. Lancet. 2024. PMID: 38101429 Free article.
Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded from the registry; people with untreated LDL cholesterol (LDL-C) of at least 13.0 mmol/L were excluded from this study. Data were assess …
Diagnoses relying on self-reported history of familial hypercholesterolaemia and suspected secondary hypercholesterolaemia were excluded fro …
The biology of the germ line in echinoderms.
Wessel GM, Brayboy L, Fresques T, Gustafson EA, Oulhen N, Ramos I, Reich A, Swartz SZ, Yajima M, Zazueta V. Wessel GM, et al. Mol Reprod Dev. 2014 Aug;81(8):679-711. doi: 10.1002/mrd.22223. Epub 2014 Jul 22. Mol Reprod Dev. 2014. PMID: 23900765 Free PMC article. Review.
SERT and BDNF polymorphisms interplay on neuroticism in borderline personality disorder.
Salinas V, Villarroel J, Silva H, Herrera L, Jerez S, Zazueta A, Montes C, Nieto R, Bustamante ML. Salinas V, et al. BMC Res Notes. 2020 Feb 7;13(1):61. doi: 10.1186/s13104-020-4924-6. BMC Res Notes. 2020. PMID: 32033618 Free PMC article.
RESULTS: We found an association with SERT, where S-allele carriers had significantly higher levels of N than L-homozygous. Furthermore, we found that the protective effect of L-homozygosity is only evident on A-allele carriers of the BDNF Val66Met polymorphism. ...
RESULTS: We found an association with SERT, where S-allele carriers had significantly higher levels of N than L-homozygous. Furthermo …
Philadelphia Chromosome-Positive De Novo Acute Myeloid Leukemia Treated With Chemotherapy and Second-Generation Tyrosine Kinase Inhibitor.
Muñoz JD, Barranco Lampón GI, Castellanos H, Ramos C, Zazueta JF. Muñoz JD, et al. Cureus. 2019 Jul 15;11(7):e5135. doi: 10.7759/cureus.5135. Cureus. 2019. PMID: 31523564 Free PMC article.
A 26-year-old male patient was referred to our hospital for an examination of anemia, thrombocytopenia (hemoglobin 5.7 g/dL and platelets 110 000/L) and elevated White Blood Cell (WBC) count (11 600 mu/L, 24% segmented, 63% lymphocytes, 11% monocytes). ...
A 26-year-old male patient was referred to our hospital for an examination of anemia, thrombocytopenia (hemoglobin 5.7 g/dL and platelets 11 …
A CRAC-like motif in BAX sequence: relationship with protein insertion and pore activity in liposomes.
Martínez-Abundis E, Correa F, Rodríguez E, Soria-Castro E, Rodríguez-Zavala JS, Pacheco-Alvarez D, Zazueta C. Martínez-Abundis E, et al. Biochim Biophys Acta. 2011 Jul;1808(7):1888-95. doi: 10.1016/j.bbamem.2011.03.008. Epub 2011 Apr 5. Biochim Biophys Acta. 2011. PMID: 21440528 Free article.
Residues 113 to 119 of the recombinant BAX alpha5-helix, LFYFASK, correspond with the sequence motif described for the consensus pattern, -L/V-(X)(1-5)-Y-(X)(1-5)-R/K. Functional characterization of the point mutations, K119A, Y115F, and L113A in BAX, was performed in lipo …
Residues 113 to 119 of the recombinant BAX alpha5-helix, LFYFASK, correspond with the sequence motif described for the consensus pattern, - …
Scintillation light detection in the 6-m drift-length ProtoDUNE Dual Phase liquid argon TPC.
Abud AA, Abi B, Acciarri R, Acero MA, Adames MR, Adamov G, Adamowski M, Adams D, Adinolfi M, Aduszkiewicz A, Aguilar J, Ahmad Z, Ahmed J, Aimard B, Ali-Mohammadzadeh B, Alion T, Allison K, Monsalve SA, AlRashed M, Alt C, Alton A, Alvarez R, Amedo P, Anderson J, Andreopoulos C, Andreotti M, Andrews M, Andrianala F, Andringa S, Anfimov N, Ankowski A, Antoniassi M, Antonova M, Antoshkin A, Antusch S, Aranda-Fernandez A, Arellano L, Arnold LO, Arroyave MA, Asaadi J, Asquith L, Aurisano A, Aushev V, Autiero D, Lara VA, Ayala-Torres M, Azfar F, Back A, Back H, Back JJ, Backhouse C, Bagaturia I, Bagby L, Balashov N, Balasubramanian S, Baldi P, Baller B, Bambah B, Barao F, Barenboim G, Alzas PB, Barker G, Barkhouse W, Barnes C, Barr G, Monarca JB, Barros A, Barros N, Barrow JL, Basharina-Freshville A, Bashyal A, Basque V, Batchelor C, Chagas EBD, Battat JBR, Battisti F, Bay F, Bazetto MCQ, Alba JLLB, Beacom JF, Bechetoille E, Behera B, Beigbeder C, Bellantoni L, Bellettini G, Bellini V, Beltramello O, Benekos N, Montiel CB, Neves FB, Berger J, Berkman S, Bernardini P, Berner RM, Bersani A, Bertolucci S, Betancourt M, Rodríguez AB, Bevan A, Bezawada Y, Bezerra TJC, Bhardwaj A, Bhatnagar V,… See abstract for full author list ➔ Abud AA, et al. Eur Phys J C Part Fields. 2022;82(7):618. doi: 10.1140/epjc/s10052-022-10549-w. Epub 2022 Jul 16. Eur Phys J C Part Fields. 2022. PMID: 35859696 Free PMC article.
Renal oxidative stress induced by long-term hyperuricemia alters mitochondrial function and maintains systemic hypertension.
Cristóbal-García M, García-Arroyo FE, Tapia E, Osorio H, Arellano-Buendía AS, Madero M, Rodríguez-Iturbe B, Pedraza-Chaverrí J, Correa F, Zazueta C, Johnson RJ, Lozada LG. Cristóbal-García M, et al. Oxid Med Cell Longev. 2015;2015:535686. doi: 10.1155/2015/535686. Epub 2015 Mar 31. Oxid Med Cell Longev. 2015. PMID: 25918583 Free PMC article.
Long-term (11-12 weeks) and short-term (3 weeks) effects of oxonic acid induced hyperuricemia were studied in rats (OA, 750 mg/kg BW), OA+Allopurinol (AP, 150 mg/L drinking water), OA+Tempol (T, 15 mg/kg BW), or vehicle. Systolic blood pressure, renal blood flow, and vascu …
Long-term (11-12 weeks) and short-term (3 weeks) effects of oxonic acid induced hyperuricemia were studied in rats (OA, 750 mg/kg BW), OA+Al …
Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade.
Hernández-Reséndiz S, Palma-Flores C, De Los Santos S, Román-Anguiano NG, Flores M, de la Peña A, Flores PL, Fernández-G JM, Coral-Vázquez RM, Zazueta C. Hernández-Reséndiz S, et al. Basic Res Cardiol. 2015 Mar;110(2):1. doi: 10.1007/s00395-015-0464-y. Epub 2015 Jan 15. Basic Res Cardiol. 2015. PMID: 25589055
In an open-chest model of 30-min ischemia and 90-min reperfusion, male Wistar rats were randomly assigned to different groups: Control, Prolame, Prolame followed by the nitric oxide synthase inhibitor (L-NAME), and 17beta-estradiol. Areas of risk, infarct size and no-reflo …
In an open-chest model of 30-min ischemia and 90-min reperfusion, male Wistar rats were randomly assigned to different groups: Control, Prol …
14 results