C─C Cleavage Approach to C─H Functionalization of Saturated Aza-Cycles.
Roque JB, Kuroda Y, Jurczyk J, Xu LP, Ham JS, Göttemann LT, Roberts CA, Adpressa D, Saurí J, Joyce LA, Musaev DG, Yeung CS, Sarpong R.
Roque JB, et al.
ACS Catal. 2020 Mar 6;10(5):2929-2941. doi: 10.1021/acscatal.9b04551. Epub 2020 Jan 16.
ACS Catal. 2020.
PMID: 33569242
Free PMC article.
The initial functionalization step is the generation of underexplored N-fused bicyclo alpha-hydroxy-beta-lactams under mild, visible light conditions using a Norrish-Yang process to affect alpha-functionalization of saturated cyclic amines. ...
The initial functionalization step is the generation of underexplored N-fused bicyclo alpha-hydroxy-beta-lactams under mild, visible light c …