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Year Number of Results
1995 1
2008 2
2009 1
2010 1
2012 1
2013 2
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2017 1
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2019 2
2021 2
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2023 2
2024 0

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17 results

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Page 1
Small-Volume Blood Collection Tubes to Reduce Transfusions in Intensive Care: The STRATUS Randomized Clinical Trial.
Siegal DM, Belley-Côté EP, Lee SF, Hill S, D'Aragon F, Zarychanski R, Rochwerg B, Chassé M, Binnie A, Honarmand K, Lauzier F, Ball I, Al-Hazzani W, Archambault P, Duan E, Khwaja K, Lellouche F, Lysecki P, Marquis F, Naud JF, Shahin J, Shea J, Tsang JLY, Wang HT, Crowther M, Arnold DM, Di Sante E, Marfo G, Kovalova T, Fonguh S, Vincent J, Connolly SJ. Siegal DM, et al. JAMA. 2023 Nov 21;330(19):1872-1881. doi: 10.1001/jama.2023.20820. JAMA. 2023. PMID: 37824152 Free PMC article. Clinical Trial.
The respiratory supercomplex from C. glutamicum.
Moe A, Kovalova T, Król S, Yanofsky DJ, Bott M, Sjöstrand D, Rubinstein JL, Högbom M, Brzezinski P. Moe A, et al. Structure. 2022 Mar 3;30(3):338-349.e3. doi: 10.1016/j.str.2021.11.008. Epub 2021 Dec 14. Structure. 2022. PMID: 34910901 Free article.
A menaquinone is bound in each of the Q(N) and Q(P) sites in each CIII and an additional menaquinone is positioned 14 A from heme b(L). A di-heme cyt. cc subunit electronically connects each CIII with an adjacent CIV, with the Rieske iron-sulfur protein positioned with the …
A menaquinone is bound in each of the Q(N) and Q(P) sites in each CIII and an additional menaquinone is positioned 14 A from heme b(L
Alpha-L-fucosidase isoenzyme iso2 from Paenibacillus thiaminolyticus.
Benešová E, Lipovová P, Krejzová J, Kovaľová T, Buchtová P, Spiwok V, Králová B. Benešová E, et al. BMC Biotechnol. 2015 May 27;15:36. doi: 10.1186/s12896-015-0160-x. BMC Biotechnol. 2015. PMID: 26013545 Free PMC article.
BACKGROUND: alpha-L-Fucosidases are enzymes involved in metabolism of alpha-L-fucosylated molecules, compounds with a fundamental role in different life essential processes including immune response, fertilization and development, but also in some serious pathologic …
BACKGROUND: alpha-L-Fucosidases are enzymes involved in metabolism of alpha-L-fucosylated molecules, compounds with a fundamen …
The first structure-function study of GH151 alpha-l-fucosidase uncovers new oligomerization pattern, active site complementation, and selective substrate specificity.
Koval'ová T, Kovaľ T, Stránský J, Kolenko P, Dušková J, Švecová L, Vodičková P, Spiwok V, Benešová E, Lipovová P, Dohnálek J. Koval'ová T, et al. FEBS J. 2022 Aug;289(16):4998-5020. doi: 10.1111/febs.16387. Epub 2022 Feb 20. FEBS J. 2022. PMID: 35113503 Free article.
According to the crystal structure, small-angle X-ray scattering data and catalytic investigation, this enzyme functions as a tetramer of a new type and represents the second known case of active site complementation among all alpha-l-fucosidases. Mutation of the active si …
According to the crystal structure, small-angle X-ray scattering data and catalytic investigation, this enzyme functions as a tetramer of a …
Characteristics and outcome of primary resistant disease in paediatric acute myeloid leukaemia.
Karlsson L, Cheuk D, De Moerloose B, Hasle H, Jahnukainen K, Juul-Dam KL, Kaspers G, Kovalova Z, Lausen B, Nyström UN, Palle J, Pronk CJ, Saks K, Tierens A, Zeller B, Abrahamsson J. Karlsson L, et al. Br J Haematol. 2023 May;201(4):757-765. doi: 10.1111/bjh.18685. Epub 2023 Feb 10. Br J Haematol. 2023. PMID: 36762836
Risk factors for RD were age10 years or older and a white-blood-cell count (WBC) of 100 10(9) /L or more at diagnosis. The five-year overall survival (OS) was 38% (95% confidence interval [CI]: 28%-52%). ...
Risk factors for RD were age10 years or older and a white-blood-cell count (WBC) of 100 10(9) /L or more at diagnosis. The five-year …
Active site complementation and hexameric arrangement in the GH family 29; a structure-function study of alpha-l-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus.
Kovalová T, Koval T, Benešová E, Vodicková P, Spiwok V, Lipovová P, Dohnálek J. Kovalová T, et al. Glycobiology. 2019 Jan 1;29(1):59-73. doi: 10.1093/glycob/cwy078. Glycobiology. 2019. PMID: 30544181
alpha-l-Fucosidase isoenzyme 1 from bacterium Paenibacillus thiaminolyticus is a member of the glycoside hydrolase family GH29 capable of cleaving l-fucose from nonreducing termini of oligosaccharides and glycoconjugates. ...
alpha-l-Fucosidase isoenzyme 1 from bacterium Paenibacillus thiaminolyticus is a member of the glycoside hydrolase family GH29 capabl …
High-Frequency Audiometry in Women with and without Exposure to Workplace Noise.
Mrázková E, Kovalová M, Čada Z, Gottfriedová N, Rychlý T, Škerková M. Mrázková E, et al. Int J Environ Res Public Health. 2021 Jun 15;18(12):6463. doi: 10.3390/ijerph18126463. Int J Environ Res Public Health. 2021. PMID: 34203734 Free PMC article.
The cohort comprised 243 women (average age 36.2 years), of which 88 women were employed in a noisy (L(Aeq,8h) 85-105 dB) workplace, while 155 women did not experience noise. ...
The cohort comprised 243 women (average age 36.2 years), of which 88 women were employed in a noisy (L(Aeq,8h) 85-105 dB) workplace, …
Ecotoxicity and genotoxicity assessment of cytotoxic antineoplastic drugs and their metabolites.
Zounkova R, Kovalova L, Blaha L, Dott W. Zounkova R, et al. Chemosphere. 2010 Sep;81(2):253-60. doi: 10.1016/j.chemosphere.2010.06.029. Epub 2010 Jul 10. Chemosphere. 2010. PMID: 20624627
Toxicity was relatively high at parent compounds with EC(50) values ranging from 44 microg L(-1) (5-fluorouracil in the P. putida test) to 200 mg L(-1) (cytarabine in D. magna acute test). ...Studied metabolites showed low or no toxicity; only FBAL (metabolite of 5- …
Toxicity was relatively high at parent compounds with EC(50) values ranging from 44 microg L(-1) (5-fluorouracil in the P. putida tes …
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo.
Effenberg R, Turánek Knötigová P, Zyka D, Čelechovská H, Mašek J, Bartheldyová E, Hubatka F, Koudelka Š, Lukáč R, Kovalová A, Šaman D, Křupka M, Barkocziova L, Kosztyu P, Šebela M, Drož L, Hučko M, Kanásová M, Miller AD, Raška M, Ledvina M, Turánek J. Effenberg R, et al. J Med Chem. 2017 Sep 28;60(18):7745-7763. doi: 10.1021/acs.jmedchem.7b00593. Epub 2017 Sep 8. J Med Chem. 2017. PMID: 28829599
Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norAbuGMDP-Lys(L18), norAbuGMDP-Lys(B30), B30 norAbuMDP, L18 norAbuMDP) are designed and synthesized comprising the normuramyl-l-alpha-am …
Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norA …
Development of arterial hypotension in premature infants with early onset bacterial infections: tools of clinical predication.
Pokhylko V, Kovalova O, Cherniavska Y, Tsvirenko S, Klymchuk Y. Pokhylko V, et al. Wiad Lek. 2019;72(5 cz 2):1068-1073. Wiad Lek. 2019. PMID: 31175746
CONCLUSION: Conclusions: The following diagnostic criteria can be used for the appointment of medical support for hemodynamics: the digital value of the level of mean blood pressure, expressed in mmHg, is less than the gestational age in weeks, and at least one of the following i …
CONCLUSION: Conclusions: The following diagnostic criteria can be used for the appointment of medical support for hemodynamics: the digital …
17 results