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Identification of subunit- and antagonist-specific amino acid residues in the N-Methyl-D-aspartate receptor glutamate-binding pocket.
Kinarsky L, Feng B, Skifter DA, Morley RM, Sherman S, Jane DE, Monaghan DT. Kinarsky L, et al. J Pharmacol Exp Ther. 2005 Jun;313(3):1066-74. doi: 10.1124/jpet.104.082990. Epub 2005 Mar 2. J Pharmacol Exp Ther. 2005. PMID: 15743930
This analysis suggested an affinity order for the PPDA isomers of d-cis > L-cis > L-trans = D-trans and predicted that the 2-position carboxylate group of the cis-PPDA isomers, but not of the trans-PPDA isomers, may be interacting with histidine 486 in NR2B. . …
This analysis suggested an affinity order for the PPDA isomers of d-cis > L-cis > L-trans = D-trans and predicted that t …
Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes.
Ninkovic T, Kinarsky L, Engelmann K, Pisarev V, Sherman S, Finn OJ, Hanisch FG. Ninkovic T, et al. Mol Immunol. 2009 Nov;47(1):131-40. doi: 10.1016/j.molimm.2008.09.032. Epub 2008 Nov 12. Mol Immunol. 2009. PMID: 19007994 Free PMC article.
In this study we show that human immunoproteasomes and cathepsin-L can generate octa to undecameric glycopeptides from the MUC1 repeat domain in vitro. ...
In this study we show that human immunoproteasomes and cathepsin-L can generate octa to undecameric glycopeptides from the MUC1 repea …
Identification of disulfide bonds among the nine core 2 N-acetylglucosaminyltransferase-M cysteines conserved in the mucin beta6-N-acetylglucosaminyltransferase family.
Singh J, Khan GA, Kinarsky L, Cheng H, Wilken J, Choi KH, Bedows E, Sherman S, Cheng PW. Singh J, et al. J Biol Chem. 2004 Sep 10;279(37):38969-77. doi: 10.1074/jbc.M401046200. Epub 2004 Jun 28. J Biol Chem. 2004. PMID: 15226299 Free article.
This pattern of disulfide bond formation differs from that of mouse C2GnT-L, which may contribute to the difference in substrate specificity between these two enzymes. ...
This pattern of disulfide bond formation differs from that of mouse C2GnT-L, which may contribute to the difference in substrate spec …