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Epistasis reduces fitness costs of influenza A virus escape from stem-binding antibodies.
Lee CY, Raghunathan V, Caceres CJ, Geiger G, Seibert B, Cargnin Faccin F, Gay LC, Ferreri LM, Kaul D, Wrammert J, Tan GS, Perez DR, Lowen AC. Lee CY, et al. Among authors: gay lc. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2208718120. doi: 10.1073/pnas.2208718120. Epub 2023 Apr 17. Proc Natl Acad Sci U S A. 2023. PMID: 37068231 Free PMC article.
Development of a Novel Live Attenuated Influenza A Virus Vaccine Encoding the IgA-Inducing Protein.
Cáceres CJ, Cardenas-Garcia S, Jain A, Gay LC, Carnaccini S, Seibert B, Ferreri LM, Geiger G, Jasinskas A, Nakajima R, Rajao DS, Isakova-Sivak I, Rudenko L, Vincent AL, Davies DH, Perez DR. Cáceres CJ, et al. Among authors: gay lc. Vaccines (Basel). 2021 Jun 27;9(7):703. doi: 10.3390/vaccines9070703. Vaccines (Basel). 2021. PMID: 34198994 Free PMC article.
Impact of sex on humoral immunity with live influenza B virus vaccines in mice.
Cardenas-Garcia S, Cáceres CJ, Jain A, Geiger G, Mo JS, Gay LC, Seibert B, Jasinskas A, Nakajima R, Rajao DS, Davies DH, Perez DR. Cardenas-Garcia S, et al. Among authors: gay lc. NPJ Vaccines. 2024 Feb 26;9(1):45. doi: 10.1038/s41541-024-00827-x. NPJ Vaccines. 2024. PMID: 38409236 Free PMC article.
Rational design of a deuterium-containing M2-S31N channel blocker UAWJ280 with in vivo antiviral efficacy against both oseltamivir sensitive and -resistant influenza A viruses.
Cáceres CJ, Hu Y, Cárdenas-García S, Wu X, Tan H, Carnaccini S, Gay LC, Geiger G, Ma C, Zhang QY, Rajao D, Perez DR, Wang J. Cáceres CJ, et al. Among authors: gay lc. Emerg Microbes Infect. 2021 Dec;10(1):1832-1848. doi: 10.1080/22221751.2021.1972769. Emerg Microbes Infect. 2021. PMID: 34427541 Free PMC article.
Amino acid 138 in the HA of a H3N2 subtype influenza A virus increases affinity for the lower respiratory tract and alveolar macrophages in pigs.
Cardenas M, Seibert B, Cowan B, Fraiha ALS, Carnaccini S, Gay LC, Faccin FC, Caceres CJ, Anderson TK, Vincent Baker AL, Perez DR, Rajao DS. Cardenas M, et al. Among authors: gay lc. PLoS Pathog. 2024 Feb 20;20(2):e1012026. doi: 10.1371/journal.ppat.1012026. eCollection 2024 Feb. PLoS Pathog. 2024. PMID: 38377132 Free PMC article.