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Covalent fragment libraries in drug discovery.
Keeley A, Petri L, Ábrányi-Balogh P, Keserű GM. Keeley A, et al. Among authors: petri l. Drug Discov Today. 2020 Jun;25(6):983-996. doi: 10.1016/j.drudis.2020.03.016. Epub 2020 Apr 13. Drug Discov Today. 2020. PMID: 32298798 Free article. Review.
Discovery of selective fragment-sized immunoproteasome inhibitors.
Kollár L, Gobec M, Szilágyi B, Proj M, Knez D, Ábrányi-Balogh P, Petri L, Imre T, Bajusz D, Ferenczy GG, Gobec S, Keserű GM, Sosič I. Kollár L, et al. Among authors: petri l. Eur J Med Chem. 2021 Jul 5;219:113455. doi: 10.1016/j.ejmech.2021.113455. Epub 2021 Apr 20. Eur J Med Chem. 2021. PMID: 33894528
Cysteine specific bioconjugation with benzyl isothiocyanates.
Petri L, Szijj PA, Kelemen Á, Imre T, Gömöry Á, Lee MTW, Hegedűs K, Ábrányi-Balogh P, Chudasama V, Keserű GM. Petri L, et al. RSC Adv. 2020 Apr 16;10(25):14928-14936. doi: 10.1039/d0ra02934c. eCollection 2020 Apr 8. RSC Adv. 2020. PMID: 35497170 Free PMC article.
Activation-Free Sulfonyl Fluoride Probes for Fragment Screening.
Petri L, Ábrányi-Balogh P, Csorba N, Keeley A, Simon J, Ranđelović I, Tóvári J, Schlosser G, Szabó D, Drahos L, Keserű GM. Petri L, et al. Molecules. 2023 Mar 29;28(7):3042. doi: 10.3390/molecules28073042. Molecules. 2023. PMID: 37049805 Free PMC article.
Next-Generation Heterocyclic Electrophiles as Small-Molecule Covalent MurA Inhibitors.
Ábrányi-Balogh P, Keeley A, Ferenczy GG, Petri L, Imre T, Grabrijan K, Hrast M, Knez D, Ilaš J, Gobec S, Keserű GM. Ábrányi-Balogh P, et al. Among authors: petri l. Pharmaceuticals (Basel). 2022 Nov 29;15(12):1484. doi: 10.3390/ph15121484. Pharmaceuticals (Basel). 2022. PMID: 36558935 Free PMC article.
Targeting an Intrinsically Disordered Protein by Covalent Modification.
Nguyen HH, Ábrányi-Balogh P, Petri L, Mészáros A, Pauwels K, Vandenbussche G, Keserű GM, Tompa P. Nguyen HH, et al. Among authors: petri l. Methods Mol Biol. 2020;2141:835-854. doi: 10.1007/978-1-0716-0524-0_43. Methods Mol Biol. 2020. PMID: 32696392
Covalent fragment mapping of KRasG12C revealed novel chemotypes with in vivo potency.
Orgován Z, Péczka N, Petri L, Ábrányi-Balogh P, Ranđelović I, Tóth S, Szakács G, Nyíri K, Vértessy B, Pálfy G, Vida I, Perczel A, Tóvári J, Keserű GM. Orgován Z, et al. Among authors: petri l. Eur J Med Chem. 2023 Mar 15;250:115212. doi: 10.1016/j.ejmech.2023.115212. Epub 2023 Feb 15. Eur J Med Chem. 2023. PMID: 36842271 Free article.
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria.
Bereczki I, Vimberg V, Lőrincz E, Papp H, Nagy L, Kéki S, Batta G, Mitrović A, Kos J, Zsigmond Á, Hajdú I, Lőrincz Z, Bajusz D, Petri L, Hodek J, Jakab F, Keserű GM, Weber J, Naesens L, Herczegh P, Borbás A. Bereczki I, et al. Among authors: petri l. Sci Rep. 2022 Sep 26;12(1):16001. doi: 10.1038/s41598-022-20182-y. Sci Rep. 2022. PMID: 36163239 Free PMC article.
Assessment of Tractable Cysteines for Covalent Targeting by Screening Covalent Fragments.
Petri L, Ábrányi-Balogh P, Tímea I, Pálfy G, Perczel A, Knez D, Hrast M, Gobec M, Sosič I, Nyíri K, Vértessy BG, Jänsch N, Desczyk C, Meyer-Almes FJ, Ogris I, Golič Grdadolnik S, Iacovino LG, Binda C, Gobec S, Keserű GM. Petri L, et al. Chembiochem. 2021 Feb 15;22(4):743-753. doi: 10.1002/cbic.202000700. Epub 2020 Nov 9. Chembiochem. 2021. PMID: 33030752
18 results