Orthodontic force-induced oxidative stress in the periodontal tissue and dental pulp elicits nociception via activation/sensitization of TRPA1 on nociceptive fibers.
Morii A, Miyamura Y, Sago MI, Mizuhara M, Shikayama T, Naniwa M, Hitomi S, Ujihara I, Kuroishi KN, Gunjigake KK, Shiga M, Morimoto Y, Kawamoto T, Ono K.
Morii A, et al.
Free Radic Biol Med. 2020 Feb 1;147:175-186. doi: 10.1016/j.freeradbiomed.2019.12.016. Epub 2019 Dec 20.
Free Radic Biol Med. 2020.
PMID: 31866360
In the PDL, the oxidative stress marker 8-OHdG was highly detected on day 1 and recovered on day 5 to the sham-operated level. The dental pulp showed similar results as the PDL. ...
In the PDL, the oxidative stress marker 8-OHdG was highly detected on day 1 and recovered on day 5 to the sham-operated level. The de …