Early unexpected failure of a vitamin E-infused highly cross-linked polyethylene liner: A case report

Medicine (Baltimore). 2021 Oct 15;100(41):e27454. doi: 10.1097/MD.0000000000027454.

Abstract

Rationale: Total hip arthroplasty (THA) with a polyethylene (PE) liner is 1 of the most effective and successful treatment strategies for end-stage hip disorders. Vitamin E-infused highly cross-linked polyethylene is theoretically known to prevent failure due to oxidative degradation in the body, and is resistant to wear; therefore, successful long-term survival of THA is expected.

Patient concerns: In June 2019, approximately 1.5 years after THA, the patient sat down and stood up without any specific issue; however, an unusual bullet sound occurred around the left hip joint. Since then, his discomfort persisted, and he was admitted to the emergency department.

Diagnosis: Plain radiography and metal artifact reduction computed tomography performed in the emergency department revealed eccentric elevation of the prosthetic femoral head and suspected PE liner failure.

Intervention: Revision surgery was performed for modular component exchange. To reduce the dislocation risk without performing cup exchange, conversion to dual-mobility articulation was performed.

Outcomes: During the regular follow-up post-surgery, the patient could perform daily life activities without any discomfort, and dislocation was not observed. At 2 years postoperatively, no significant changes were observed in the radiographic images.

Lessons: This case report presents an unexpected failure of THA due to superior rim fracture and excessive wear at the locking mechanism of the vitamin E-infused highly cross-linked polyethylene liner. This is an interesting case, as early PE liner failure occurred without strong labor intensity or trauma. A modular component exchange was performed with a dual-mobility bearing, and no issues were observed approximately 2 years after the reoperation. Therefore, third-generation highly cross-linked polyethylene liners can also cause early failure without a clear cause, and this case report highlights the necessity of considering several strategies for reoperation.

Study design: Case report.

Publication types

  • Case Reports

MeSH terms

  • Arthroplasty, Replacement, Hip / adverse effects*
  • Hip Prosthesis / adverse effects
  • Humans
  • Male
  • Middle Aged
  • Polyethylene
  • Prosthesis Design
  • Prosthesis Failure / adverse effects*
  • Reoperation
  • Vitamin E

Substances

  • Vitamin E
  • Polyethylene