Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2017 1
2023 1
2024 1

Text availability

Article attribute

Article type

Publication date

Search Results

2 results

Results by year

Filters applied: . Clear all
Page 1
Did you mean kwanghyok son (1 results)?
Discovery of novel [1,2,4]triazolo[4,3-a]quinoxaline aminophenyl derivatives as BET inhibitors for cancer treatment.
Ali I, Lee J, Go A, Choi G, Lee K. Ali I, et al. Bioorg Med Chem Lett. 2017 Oct 15;27(20):4606-4613. doi: 10.1016/j.bmcl.2017.09.025. Epub 2017 Sep 14. Bioorg Med Chem Lett. 2017. PMID: 28939121
The substantial antiproliferative activities in human cancer cell lines, promising drug-like properties, and the selectivity for the BET family make the lead compound (13) as a novel BRD4 inhibitor motif for anti-cancer drug discovery....
The substantial antiproliferative activities in human cancer cell lines, promising drug-like properties, and the selectivity for the BET …
DW71177: A novel [1,2,4]triazolo[4,3-a]quinoxaline-based potent and BD1-Selective BET inhibitor for the treatment of acute myeloid leukemia.
Ali I, Cha HJ, Lim B, Chae CH, Youm J, Park WJ, Lee SH, Kim JH, Jeong D, Lim JK, Hwang YH, Roe JS, Woo JS, Lee K, Choi G. Ali I, et al. Eur J Med Chem. 2024 Feb 5;265:116052. doi: 10.1016/j.ejmech.2023.116052. Epub 2023 Dec 16. Eur J Med Chem. 2024. PMID: 38134745 Free article.
The bromodomain and extraterminal domain (BET) family proteins recognize acetyl-lysine (K(ac)) at the histone tail through two tandem bromodomains, i.e., BD1 and BD2, to regulate gene expression. ...
The bromodomain and extraterminal domain (BET) family proteins recognize acetyl-lysine (K(ac)) at the histone tail through two tandem …