Abstract
A highly enantioselective conjugate addition of nitroalkanes to enones has been developed. The process is efficiently catalyzed by a simple chiral cyclohexanediamine-derived primary amine thiourea with a broad substrate scope.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Alkanes / chemistry
-
Amines / chemistry*
-
Catalysis
-
Cyclohexylamines / chemistry*
-
Ketones / chemical synthesis*
-
Ketones / chemistry*
-
Molecular Structure
-
Nitro Compounds / chemical synthesis*
-
Nitro Compounds / chemistry
-
Stereoisomerism
-
Thiourea / chemistry*
Substances
-
Alkanes
-
Amines
-
Cyclohexylamines
-
Ketones
-
Nitro Compounds
-
1,2-cyclohexanediamine
-
Thiourea