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Efficacy of an unmodified bivalent mRNA vaccine against SARS-CoV-2 variants in female small animal models.
Corleis B, Hoffmann D, Rauch S, Fricke C, Roth N, Gergen J, Kovacikova K, Schlottau K, Halwe NJ, Ulrich L, Schön J, Wernike K, Widera M, Ciesek S, Mueller SO, Mettenleiter TC, Maione D, Petsch B, Beer M, Dorhoi A. Corleis B, et al. Among authors: kovacikova k. Nat Commun. 2023 Feb 13;14(1):816. doi: 10.1038/s41467-023-36110-1. Nat Commun. 2023. PMID: 36781853 Free PMC article.
Design, Synthesis, and Anti-RNA Virus Activity of 6'-Fluorinated-Aristeromycin Analogues.
Yoon JS, Kim G, Jarhad DB, Kim HR, Shin YS, Qu S, Sahu PK, Kim HO, Lee HW, Wang SB, Kong YJ, Chang TS, Ogando NS, Kovacikova K, Snijder EJ, Posthuma CC, van Hemert MJ, Jeong LS. Yoon JS, et al. Among authors: kovacikova k. J Med Chem. 2019 Jul 11;62(13):6346-6362. doi: 10.1021/acs.jmedchem.9b00781. Epub 2019 Jun 20. J Med Chem. 2019. PMID: 31244113 Free PMC article.
Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery.
Abdelnabi R, Kovacikova K, Moesslacher J, Donckers K, Battisti V, Leyssen P, Langer T, Puerstinger G, Quérat G, Li C, Decroly E, Tas A, Marchand A, Chaltin P, Coutard B, van Hemert M, Neyts J, Delang L. Abdelnabi R, et al. Among authors: kovacikova k. Antimicrob Agents Chemother. 2020 Jun 23;64(7):e00649-20. doi: 10.1128/AAC.00649-20. Print 2020 Jun 23. Antimicrob Agents Chemother. 2020. PMID: 32340991 Free PMC article.
Structural Insights into the Mechanisms of Action of Functionally Distinct Classes of Chikungunya Virus Nonstructural Protein 1 Inhibitors.
Kovacikova K, Gorostiola González M, Jones R, Reguera J, Gigante A, Pérez-Pérez MJ, Pürstinger G, Moesslacher J, Langer T, Jeong LS, Delang L, Neyts J, Snijder EJ, van Westen GJP, van Hemert MJ. Kovacikova K, et al. Antimicrob Agents Chemother. 2021 Jun 17;65(7):e0256620. doi: 10.1128/AAC.02566-20. Epub 2021 Jun 17. Antimicrob Agents Chemother. 2021. PMID: 33875421 Free PMC article.
6'-β-Fluoro-Homoaristeromycin and 6'-Fluoro-Homoneplanocin A Are Potent Inhibitors of Chikungunya Virus Replication through Their Direct Effect on Viral Nonstructural Protein 1.
Kovacikova K, Morren BM, Tas A, Albulescu IC, van Rijswijk R, Jarhad DB, Shin YS, Jang MH, Kim G, Lee HW, Jeong LS, Snijder EJ, van Hemert MJ. Kovacikova K, et al. Antimicrob Agents Chemother. 2020 Mar 24;64(4):e02532-19. doi: 10.1128/AAC.02532-19. Print 2020 Mar 24. Antimicrob Agents Chemother. 2020. PMID: 31964798 Free PMC article.
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