Abstract
Two fluorescent streptocyanine labelled oligonucleotides have been synthesized by a simple "click" reaction between a non-fluorescent hemicarboxonium salt and aminoalkyl functionalized thymidines within the oligonucleotide and their spectrophotometric properties have been studied.
MeSH terms
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Base Sequence
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Carbocyanines / chemical synthesis*
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Carbocyanines / chemistry
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Click Chemistry
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Fluorescent Dyes / chemical synthesis*
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Fluorescent Dyes / chemistry
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Genotyping Techniques
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Humans
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Polymorphism, Single Nucleotide
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Thymidine / analogs & derivatives*
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Thymidine / chemical synthesis*
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Thymidine / chemistry
Substances
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Carbocyanines
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Fluorescent Dyes
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Thymidine