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2016 3
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Page 1
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in an Alzheimer's disease mouse model.
Tallon C, Bell BJ, Malvankar MM, Deme P, Nogueras-Ortiz C, Eren E, Thomas AG, Hollinger KR, Pal A, Mustapic M, Huang M, Coleman K, Joe TR, Rais R, Haughey NJ, Kapogiannis D, Slusher BS. Tallon C, et al. Among authors: hollinger kr. Transl Neurodegener. 2023 Dec 4;12(1):56. doi: 10.1186/s40035-023-00383-9. Transl Neurodegener. 2023. PMID: 38049923 Free PMC article.
Inhibiting tau-induced elevated nSMase2 activity and ceramides is therapeutic in murine Alzheimer's disease.
Tallon C, Bell BJ, Malvankar MM, Deme P, Nogueras-Ortiz C, Eren E, Thomas AG, Hollinger KR, Pal A, Mustapic M, Huang M, Coleman K, Joe TR, Rais R, Haughey NJ, Kapogiannis D, Slusher BS. Tallon C, et al. Among authors: hollinger kr. Res Sq [Preprint]. 2023 Jul 18:rs.3.rs-3131295. doi: 10.21203/rs.3.rs-3131295/v1. Res Sq. 2023. PMID: 37502930 Free PMC article. Updated. Preprint.
Dendrimer-Conjugated nSMase2 Inhibitor Reduces Tau Propagation in Mice.
Tallon C, Bell BJ, Sharma A, Pal A, Malvankar MM, Thomas AG, Yoo SW, Hollinger KR, Coleman K, Wilkinson EL, Kannan S, Haughey NJ, Kannan RM, Rais R, Slusher BS. Tallon C, et al. Among authors: hollinger kr. Pharmaceutics. 2022 Sep 28;14(10):2066. doi: 10.3390/pharmaceutics14102066. Pharmaceutics. 2022. PMID: 36297501 Free PMC article.
Neutral sphingomyelinase 2 inhibition attenuates extracellular vesicle release and improves neurobehavioral deficits in murine HIV.
Zhu X, Hollinger KR, Huang Y, Borjabad A, Kim BH, Arab T, Thomas AG, Moniruzzaman M, Lovell L, Turchinovich A, Witwer KW, Volsky DJ, Haughey NJ, Slusher BS. Zhu X, et al. Among authors: hollinger kr. Neurobiol Dis. 2022 Jul;169:105734. doi: 10.1016/j.nbd.2022.105734. Epub 2022 Apr 21. Neurobiol Dis. 2022. PMID: 35462006 Free PMC article.
Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis.
Hollinger KR, Sharma A, Tallon C, Lovell L, Thomas AG, Zhu X, Wiseman R, Wu Y, Kambhampati SP, Liaw K, Sharma R, Rojas C, Rais R, Kannan S, Kannan RM, Slusher BS. Hollinger KR, et al. Nanotheranostics. 2022 Jan 1;6(2):126-142. doi: 10.7150/ntno.63158. eCollection 2022. Nanotheranostics. 2022. PMID: 34976589 Free PMC article.
Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease.
Šála M, Hollinger KR, Thomas AG, Dash RP, Tallon C, Veeravalli V, Lovell L, Kögler M, Hřebabecký H, Procházková E, Nešuta O, Donoghue A, Lam J, Rais R, Rojas C, Slusher BS, Nencka R. Šála M, et al. Among authors: hollinger kr. J Med Chem. 2020 Jun 11;63(11):6028-6056. doi: 10.1021/acs.jmedchem.0c00278. Epub 2020 May 27. J Med Chem. 2020. PMID: 32298582 Free PMC article.
Glutamine antagonism attenuates physical and cognitive deficits in a model of MS.
Hollinger KR, Smith MD, Kirby LA, Prchalova E, Alt J, Rais R, Calabresi PA, Slusher BS. Hollinger KR, et al. Neurol Neuroimmunol Neuroinflamm. 2019 Aug 29;6(6):e609. doi: 10.1212/NXI.0000000000000609. Print 2019 Nov. Neurol Neuroimmunol Neuroinflamm. 2019. PMID: 31467038 Free PMC article.
16 results