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Single Application of Low-Dose, Hydroxyapatite-Bound BMP-2 or GDF-5 Induces Long-Term Bone Formation and Biomechanical Stabilization of a Bone Defect in a Senile Sheep Lumbar Osteopenia Model.
Biomedicines. 2022 Feb 21;10(2):513. doi: 10.3390/biomedicines10020513.
Biomedicines. 2022.
PMID: 35203721
Free PMC article.
BMP-2 (and partially GDF-5) coating significantly accelerates and augments bone formation close to hydroxyapatite/tricalcium-phosphate/brushite implant cylinders for tibial bone defects in senile, osteopenic sheep.
Sachse A, Hasenbein I, Hortschansky P, Schmuck KD, Maenz S, Illerhaus B, Kuehmstedt P, Ramm R, Huber R, Kunisch E, Horbert V, Gunnella F, Roth A, Schubert H, Kinne RW.
Sachse A, et al. Among authors: schmuck kd.
J Mater Sci Mater Med. 2023 Jun 28;34(7):31. doi: 10.1007/s10856-023-06734-2.
J Mater Sci Mater Med. 2023.
PMID: 37378714
Free PMC article.
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