Fertility of Cryptorchid Testis-An Unsolved Mistery

Genes (Basel). 2021 Nov 26;12(12):1894. doi: 10.3390/genes12121894.

Abstract

Cryptorchidism (undescended testis) is one of the most common diagnoses in the pediatric urologist office. Even in the modern era, there still are a lot of debates regarding the optimal time for surgery related to the expected results in relation with the testicular function, including fertility. The review below intends to clarify issues regarding the impact of cryptorchidism on testicular histology and function, semen analysis, the relation between hormonal and surgical treatment, future fertility, and paternity rate.

Keywords: GnRH; cryptorchidism; fertility; hormonal; orchidopexy; spermatogonia; testis; undescended testis.

Publication types

  • Review

MeSH terms

  • Animals
  • Cryptorchidism / pathology*
  • Humans
  • Infertility, Male / pathology*
  • Male
  • Semen Analysis / methods
  • Testis / pathology*